879-65-2, 2-Quinoxalinecarboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,879-65-2
In a round bottomed flask, thionyl chloride (8.5 mL, 117 mmol) was added to methanol (60 mL) and the resulting solution was cooled to 0 C. Quinoxaline-2-carboxylic acid 1 (5 g, 28.7 mmol) was then added by small portions over 5 min. At the end of the addition, the mixture was returned to ambient temperature and stirred overnight. The progress of the reaction could be followed by TLC (dichloromethane/methanol: 25/1). At the end of the reaction, the solvent and excessthionyl chloride were evaporated under reduced pressure and the crude residue was neutralized with Na2CO3 (saturated solution, 30 mL). The product was extracted with dichloromethane (520 mL). The combined organic layers were washed with brine and dried over MgSO4. After filtration, the solvent was evaporated to dryness. The methyl ester 2 was obtained as a brown powder.
As the paragraph descriping shows that 879-65-2 is playing an increasingly important role.
Reference£º
Article; Maj, Anna M.; Heyte, Svetlana; Araque, Marcia; Dumeignil, Franck; Paul, Sebastien; Suisse, Isabelle; Agbossou-Niedercorn, Francine; Tetrahedron; vol. 72; 10; (2016); p. 1375 – 1380;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider