98416-72-9, 6-Bromo-2-chloro-3-methylquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,98416-72-9
4.14 4-(-6-Bromo-3-methylquinoxalin-2-yloxy)benzaldehyde (14) p-Hydroxybenzaldehyde (0.01 mol) was dissolved in a mixture of acetonitrile (50 mL) and DMF (5 mL) containing anhydrous potassium carbonate (2.0 g). The mixture was refluxed for 1 h, then compound (5, 0.01 mol) was added and the mixture was further refluxed for 19 h (monitored by TLC). After completion of the reaction, the mixture was filtered and the excess of acetonitrile was evaporated under reduced pressure, dried and crystallized from mixture of benzene and petroleum ether to yield the crude product. Yield: 76%; (orange-brown powder): mp 101-103 C; IR (KBr) numax in cm-1: 2921 (aliphatic C-H), 2837, 2720 (CH-aldehyde), 1697 (C=O), 1597 (C=N); 1H NMR (DMSO-d6, 500 MHz): delta 2.74 (s, 3H, CH3), 7.58-8.04 (m, 7H, Ar-H), 10.04 (s, 1H, CHO); 13C NMR (DMSO-d6, 125 MHz): delta 20.49 (CH3), 122.47-133.54 (12Ar-C), 148.90, 149.52 (2C=N), 190.87 (CHO); MS (m/z), 342 (M+; 100%), 343 (M++1; 27%), 344 (M++2; 96%). Anal. Calcd for C16H11BrN2O2 (343.17): C, 56.00; H, 3.23; N, 8.16. Found: C, 56.19; H, 3.45; N.
98416-72-9 6-Bromo-2-chloro-3-methylquinoxaline 13487186, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Article; Abbas, Hebat-Allah S.; Al-Marhabi, Aisha R.; Eissa, Sally I.; Ammar, Yousry A.; Bioorganic and Medicinal Chemistry; vol. 23; 20; (2015); p. 6560 – 6572;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider