With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.879-65-2,2-Quinoxalinecarboxylic acid,as a common compound, the synthetic route is as follows.
879-65-2, EXAMPLE 183 N-{4-[4-amino-2-(2-methoxyethyl)-1H-imidazo [4,5-c]quinolin-1-yl]butyl}quinoxaline-2-carboxamide Using the general method of Example 181 1-(4-aminobutyl)-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine (1.5 g, 4.78 mmol) was reacted with 2-quinoxalinecarboxylic acid (1.0 g, 5.74 mmol) to provide 270 mg of N-{4-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]butyl}quinoxaline-2-carboxamide as a yellow crystalline solid, m.p. 85-87 C. Analysis: Calculated for C26H27N7O2: % C, 66.51; % H, 5.80; % N, 20.88. Found: % C, 66.12; % H, 5.70; % N, 20.62.
As the paragraph descriping shows that 879-65-2 is playing an increasingly important role.
Reference£º
Patent; 3M Innovative Properties Company; US6756382; (2004); B2;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider