36856-91-4, 2-Bromoquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
c. Preparation of compound 6c A 25-mL round bottom flask equipped with a magnetic stirrer, a condenser and a nitrogen in/outlet adapter was charged with 2-bromoquinoxaline (13 mg, 0.063 mmol), boronate ester 6b (25 mg, 0.063 mmol), water/dioxane (1.0 mL/4.0 ml), K2C03 (17 mg, 0.126 mmol). The resulting solution was degassed for 15 min, then Pd(PPh3)4 (5 mg) was added. The reaction mixture was warmed to 100C and stirred for 1 h. After cooled to room temperature, the reaction mixture was diluted with EtOAc and washed with saturated NaHC03, brine, dried over Na2S04. The organic layer was concentrated under reduced pressure and purified on silica gel. Elution with 10 % EtOAc/hexanes solvent system afforded the desired compound (15 mg, 60 % yield) . 1H NMR (300 MHz, CDC13) delta 9.46 (s, 1H), 8.83 (s, 1H), 8.69 (m, 1H), 8.46 (s, 1H), 8.21 (m, 2H), 7.86 (m, 2H), 7.72 (d, J =12.0 Hz, 2H), 7.58 (d, J= 12.0 Hz, 2H), 4.05 (s, 3H), 1.42 (s, 9H).
36856-91-4, 36856-91-4 2-Bromoquinoxaline 582225, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Patent; RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY; LAVOIE, Edmond, J.; PARHI, Ajit; PILCH, Daniel, S.; KAUL, Malvika; WO2013/106756; (2013); A2;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider