1204-75-7, 3-Oxo-3,4-dihydroquinoxaline-2-carboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution OF 4- [ (4-BROMOPHENYL) (ethoxyimino) methyl]-1- (4-methyl-4- piperidinyl) piperidine (100 mg, 0.24 MMOL), 3-hydroxy-2-quinoxalinecarboxylic acid (56 mg, 0.29 MMOL) and ET3N (87 mg, 0.86 MMOL) in DMF (6 mL), HATU (119 mg, 0.31 MMOL) was added at room temperature and the reaction was stirred for 24h. The reaction mixture was poured into ice water and the first crop of solid was collected by filtration. The water layer was extracted with ethyl acetate and the organic layer was washed with NAHC03, dried and concentrated to give the second crop of solid. The two crops of crude were combined and purified by flash chromatography (2% to 10%, MEOH/CH2CI2) to afford the title compound as an orange solid. MS 579 (M+).
1204-75-7, The synthetic route of 1204-75-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SCHERING AKTIENGESELLSCHAFT; WO2004/113323; (2004); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider