Flexible application of in synthetic route 221012-82-4

From this literature《Studies on the rhodium- and ruthenium-catalyzed asymmetric hydrogenation of α-dehydroamino acids using a family of chiral dipyridylphosphine ligand (P-Phos)》,we know some information about this compound(221012-82-4)Name: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine, but this is not all information, there are many literatures related to this compound(221012-82-4).

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wu, Jing; Pai, Cheng Chao; Kwok, Wai Him; Guo, Rong Wei; Au-Yeung, Terry T. L.; Yeung, Chi Hung; Chan, Albert S. C. researched the compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine( cas:221012-82-4 ).Name: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine.They published the article 《Studies on the rhodium- and ruthenium-catalyzed asymmetric hydrogenation of α-dehydroamino acids using a family of chiral dipyridylphosphine ligand (P-Phos)》 about this compound( cas:221012-82-4 ) in Tetrahedron: Asymmetry. Keywords: acetamidoarylacrylate asym hydrogenation; dehydroamino acid asym hydrogenation; phenylalanine derivative enantiopure preparation; hydrogenation catalyst chiral dipyridylphosphine rhodium ruthenium preparation. We’ll tell you more about this compound (cas:221012-82-4).

The applications of the chiral dipyridylphosphine ligands I [Ar = Ph, C6H4Me-4, C6H3(Me)2-3,5] in Ru- and Rh-catalyzed hydrogenations of a variety of (Z)-2-acetamido-3-arylacrylates RCH:C(NHCOMe)CO2R1 (R = Ph, C6H4Cl-2, C6H4Cl-3, C6H4Cl-4, C6H4Me-4, C6H4OMe-4, R1 = H, Me) have been studied systematically. The results show that the electronic and steric properties of these ligands have significant influences on the enantioselectivity of the reduction Rh and Ru complexes of the same dipyridylphosphine ligand family exhibit different trends in enantioselectivity toward the same substrate.

From this literature《Studies on the rhodium- and ruthenium-catalyzed asymmetric hydrogenation of α-dehydroamino acids using a family of chiral dipyridylphosphine ligand (P-Phos)》,we know some information about this compound(221012-82-4)Name: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine, but this is not all information, there are many literatures related to this compound(221012-82-4).

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider