Little discovery in the laboratory: a new route for 19777-66-3

After consulting a lot of data, we found that this compound(19777-66-3)Safety of (S)-Propane-1,2-diamine dihydrochloride can be used in many types of reactions. And in most cases, this compound has more advantages.

Safety of (S)-Propane-1,2-diamine dihydrochloride. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: (S)-Propane-1,2-diamine dihydrochloride, is researched, Molecular C3H12Cl2N2, CAS is 19777-66-3, about Stereochemical studies of adrenergic drugs. Optically active derivatives of imidazolines. Author is Miller, Duane D.; Hsu, Fu-Lian; Ruffolo, Robert R. Jr.; Patil, Popat N..

The reaction of the appropriate diaminopropane isomer with Et 1-naphthyliminoacetate-HCl [43002-67-1] gave (R)-(+)- [(R)-I] [60397-66-2] and (S)-(-)-4-methyl-2-(1-naphthylmethyl)imidazoline-HCl [(S)-I] [60397-62-8]. The parent compound, naphazoline [835-31-4], is a potent α-adrenoreceptor agonist, (R)-I and (S)-I are moderately potent antagonists (pA2 = 5.6 and 5.8, resp.) of α-adrenoreceptor compounds and had weak antihistamine activity in the rabbit aorta.

After consulting a lot of data, we found that this compound(19777-66-3)Safety of (S)-Propane-1,2-diamine dihydrochloride can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider