Makhloufi, A.; Baitiche, M.; Merbah, M.; Benachour, D. published the artcile< Synthesis of new quinoxaline derivatives>, Related Products of 89898-96-4, the main research area is hydroxyquinoxaline alkyl aminoalkyl halide alkylation; quinoxaline derivative preparation.
New quinoxaline derivatives were prepared by the reaction of 2-hydroxyquinoxaline (I) and alkyl or alkylaminoalkyl halides in DMF using potassium carbonate as a base. The hydroxyl group was readily converted into a thiol function by treatment with phosphorus pentasulfide and/or Lawesson’s reagent in pyridine, and the subsequent alkylation of the thiol group was carried out under phase-transfer catalyst conditions. Chlorination of I was carried out with phosphorus oxychloride. Branching of alkylamino side chains to the 2-OH, 2-SH, and 2-Cl quinoxalines resulted in the synthesis of several compounds Synthesis and alkylation of 2-hydroxy 7-nitroquinoxaline were also reported.
Synthetic Communications published new progress about Alkylation. 89898-96-4 belongs to class quinoxaline, and the molecular formula is C8H5N3O3, Related Products of 89898-96-4.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider