With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1204-75-7,3-Oxo-3,4-dihydroquinoxaline-2-carboxylic acid,as a common compound, the synthetic route is as follows.
1204-75-7, Step E (Compound 5) [00138] 3-Hydroxy-2-quinoxalinecarboxylic acid (2.86 g. /15.0 mmol. ) was suspended in ethanol (75 ml. ). Added (slowly.) was concentrated sulfuric acid (5.0 ml. ) and the reaction mixture was allowed to stir at room temperature overnight. The precipitated product was filtered off and dried under reduced pressure. No further purification, material used as is. Yield: 2.15 g. LC/MS data-Retention time: 1.89 min. in 10-90 gradient. MS+: 219.2.
1204-75-7 3-Oxo-3,4-dihydroquinoxaline-2-carboxylic acid 71001, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Patent; VERTEX PHARMACEUTICALS INCORPORATED; WO2005/56547; (2005); A2;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider