Electrochemical Minisci reaction via HAT-driven 伪-C(sp3)-H functionalization of alcohols was written by Li, Heng;Tong, Jinwen;Zhu, Yan;Jiang, Cong;Liu, Ping;Sun, Peipei. And the article was included in Green Chemistry in 2022.Safety of 2-Quinoxalinol This article mentions the following:
An efficient electrochem. Minisci reaction to access 3-hydroxyalkylquinoxalin-2(1H)-ones involving hydrogen-atom transfer (HAT) driven 伪-C(sp3)-H functionalization of alcs. was achieved. Transition metal- and chem. oxidant-free conditions were the attractive synthetic features. The hydrogen atom transfer agent was hydrazoic acid generated from TMSN3 in this transformation. Primary or secondary alcs. and a wide range of quinoxalinones were found to be compatible, providing the corresponding 3-hydroxyalkylquinoxalin-2(1H)-ones in good yields. In the experiment, the researchers used many compounds, for example, 2-Quinoxalinol (cas: 1196-57-2Safety of 2-Quinoxalinol).
2-Quinoxalinol (cas: 1196-57-2) belongs to quinoxaline derivatives. Quinoxaline derivatives are important constituents of pharmacologically active compounds, including as well as for RNA synthesis inhibition, reactive dyes and pigments, azo dyes, flurox Cylin Dyes, Corrosion Inhibitors and Photovoltaic Polymers. The antitumoral properties of quinoxaline compounds have been of interest. Recently, quinoxaline and its analogs have been investigated as the catalyst’s ligands.Safety of 2-Quinoxalinol
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider