Periocular allergic contact dermatitis caused by brinzolamide was written by Navarro-Trivino, Francisco J.;Ruiz-Villaverde, Ricardo. And the article was included in Contact Dermatitis in 2021.Category: quinoxaline This article mentions the following:
A 52-yr-old woman was referred to our Contact Eczema Department with right-sided, chronic, periocular eczema that had developed over the past 12 mo. Ocular contact dermatitis caused by brinzolamide was diagnosed. ACD can involve the eyelids and/or conjunctiva, associated, or not, with chronic conjunctivitis or keratoconjunctivitis. Patch testing is the standard method for diagnosis of periocular ACD. It is recommended to test the ophthalmic medication (active ingredient) in addition to the excipients (mainly the preservatives). In the experiment, the researchers used many compounds, for example, 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine (2R,3R)-2,3-dihydroxysuccinate (cas: 70359-46-5Category: quinoxaline).
5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine (2R,3R)-2,3-dihydroxysuccinate (cas: 70359-46-5) belongs to quinoxaline derivatives. Quinoxaline is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. The antitumoral properties of quinoxaline compounds have been of interest. Recently, quinoxaline and its analogs have been investigated as the catalyst’s ligands.Category: quinoxaline
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider