Visible-light-driven cyanoalkylation of quinoxalinones using cyclobutanone oxime esters as the radical precursors was written by Zhao, Bin;Kong, Xianqiang;Xu, Bo. And the article was included in Tetrahedron Letters in 2019.Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one This article mentions the following:
We have developed a versatile visible-light-driven cyanoalkylation of quinoxalinones under mild conditions. First, the cyanoalkyl radicals are generated from readily available cyclobutanone oxime esters under blue light irradiation Then the generated radicals react with heterocycles such as quinoxalinones to give the final cyanoalkylation products. The protocol tolerates a wide range of functional groups. Our cyanoalkylation protocol does not need cyanide-based reagents and also does not need external oxidants. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one).
6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. The antitumoral properties of quinoxaline compounds have been of interest. Recently, quinoxaline and its analogs have been investigated as the catalyst’s ligands.Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider