Category: 1127-45-3

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about A lipase-glucose oxidase system for the efficient oxidation of N-heteroaromatic compounds and tertiary amines.Computed Properties of C9H7NO2.

In this work, a lipase-glucose oxidase system was designed and proven to be an efficient system for the oxidation of N-heteroaromatic compounds and tertiary amines. This dual-enzyme system not only displayed environmental friendliness, but also demonstrated its huge potential in industrial applications.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Effects of substituents on the intramolecular hydrogen bond in 8-quinolinol-N-oxides, published in 1980-10-31, which mentions a compound: 1127-45-3, Name is 8-Hydroxyquinoline 1-oxide, Molecular C9H7NO2, SDS of cas: 1127-45-3.

IR spectral and deuteration studies on 8-quinolinol-N-oxides and its 5-nitro-, 5-nitroso-, 5-amino-, 5-phenylazo-, 5,7-dibromo- and 5,7-diiodo-derivatives in solid and in solution state confirm the presence of a strong intramol. unsym. H bond involving the hydroxyl hydrogen atom and the N-oxide oxygen atom. The structure of the complex absorption pattern in the region 2850 cm-1-1800 cm-1 is explained in terms of Fermi resonance interaction between the νOH of O-H…O and the overtone and combination bands of (δOH + νC-O) and other fundamental vibrations of the mol. The absence of any significant absorptions in the νOH region in the spectra of 5,7-dichloro- and 5,7-dinitro-derivatives coupled with strong and broad absorption in 1500 cm-1-600 cm-1 region is perhaps due to the presence of very short hydrogen bonds in these compounds

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Sigler, K.; Gaskova, D.; Chladkova, K.; Knebl, R.; Wimmer, T.; Vacata, V.; Gebel, J. researched the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ).Quality Control of 8-Hydroxyquinoline 1-oxide.They published the article 《Standardized system for quantifying residual dirt on medical appliances cleansed in hospital washers-disinfectors: Dirt detection by different methods》 about this compound( cas:1127-45-3 ) in Folia Microbiologica (Prague, Czech Republic). Keywords: quantification residual dirt medical appliance hospital; disinfection surgical appliance residual dirt quantification; cleansing surgical appliance residual dirt quantification. We’ll tell you more about this compound (cas:1127-45-3).

An easy-to construct, easy-to-operate standardized system was developed for determining the residual biol. contamination of surgical instruments, endoscopes and other medical appliances subjected to hospital cleansing and/or disinfection. It consists of standard-sized pieces of glass, metal or endoscope plastic – dirt carriers – either bare or enclosed in truncated Eppendorf caps to simulate hard-to-access conditions. The surface of the carriers is covered with model dirt simulating biol. contamination and the carriers are then affixed to sturdy metal holders. Conventional model dirts were found to peel or flake off the carrier surface, lowering the precision of residual soil determination A newly developed model dirt consisting of liver mash, lactose and sunflower oil and exhibiting low tendency to peel off surfaces was therefore used. The whole setup was subjected to chem. or enzymic cleansing programs at elevated temperature in hospital washer-disinfectors of two types, and the residual dirt after cleansing was determined by three methods. The method using toxicant-doped dirt that quenches the luminescence of an indicator bacterium Photobacterium phosphoreum gave satisfactory data under laboratory conditions but with hospital-washed samples it exhibited excessive fluctuations caused by bacterium-dirt interactions and by phys. influences. Both other methods gave better results but displayed some process sensitivity. The luciferin-luciferase-based ATP bioluminescence assay sometimes gave low or even neg. dirt level values and showed a low effect of reduced dirt accessibility on cleansing of metal carriers. The Bradford protein assay showed about equal cleansing efficiency for both easily and poorly accessible carriers after enzymic cleansing. Our system can be used for determining low levels of residual contamination of medical appliances after cleansing/disinfection and assessing the efficiency of com. washer-disinfectors; its efficiency can be further increased by using a cleansing process-insensitive method for soil detection and quantification.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Name: 8-Hydroxyquinoline 1-oxide. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about Hypervalent Iodine(III)-Mediated Regioselective Cyanation of Quinoline N-Oxides with Trimethylsilyl Cyanide. Author is Xu, Feng; Li, Yuqin; Huang, Xin; Fang, Xinjie; Li, Zhuofei; Jiang, Hongshuo; Qiao, Jingyi; Chu, Wenyi; Sun, Zhizhong.

A regioselective cyanation of quinoline N-oxides with trimethylsilyl cyanide was developed by using (Diacetoxyiodo) benzene (PIDA) as mediated hypervalent iodine(III) reagent under metal-free and base-free reaction conditions to obtain 2-cyanoquinolines. The efficient PIDA reagent could play the role of an activator of the substrates and an accelerator of N-O bond cleavage. The reaction system featured a wide range of substrate suitability and high yields. The procedure was enlarged gram-scale to synthesize the tuberculosis (TB) inhibitor. Finally, according to some exptl. results, a plausible mechanism for the cyanation reaction is proposed.

There is still a lot of research devoted to this compound(SMILES：OC1=CC=CC2=CC=C[N+]([O-])=C12)Name: 8-Hydroxyquinoline 1-oxide, and with the development of science, more effects of this compound(1127-45-3) can be discovered.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Biochemical studies on quinoline derivatives. VII. Metabolic products of 8-quinolinol N-oxide》. Authors are Ito, Ryoji; Otaka, Hajime; Usui, Shigeru; Hashimoto, Yukichi.The article about the compound:8-Hydroxyquinoline 1-oxidecas:1127-45-3,SMILESS:OC1=CC=CC2=CC=C[N+]([O-])=C12).Synthetic Route of C9H7NO2. Through the article, more information about this compound (cas:1127-45-3) is conveyed.

cf. CA 56, 13486h. Main metabolic products of 8-quinolinol N-oxide (I) found in the urine of injected rabbits were 8-hydroxy-2-quinolone (II) and 7,8-dihydroxy-2-quinolone. 8,x-dihydroxy-2-quinolone, a product of further metabolism of 8-hydroxy-4-quinolone, an alkylated derivative of quinoline, and a compound of unknown structure were also found: 8-Quinolinol (III), 7,8-dihydroxyquinoline (IV), IV N-oxide, 8-quinolylsulfuric acid (V), V N-oxide, and I were not present. All other metabolic products, except a part of II, occurred in urine as glucuronides or ethereal sulfates. Metabolic products were in accord with those of II, but very different from those of III. In vitro oxidation of I by quinoline dehydrogenase was very difficult, and oxidation products were not detected.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Safety of 8-Hydroxyquinoline 1-oxide. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about Iodine-Catalyzed Direct C-H Alkenylation of Azaheterocycle N-Oxides with Alkenes. Author is Zhang, Zhenhao; Pi, Chao; Tong, Heng; Cui, Xiuling; Wu, Yangjie.

An efficient and regioselective alkenylation of azaheterocycle N-oxides with alkenes catalyzed by iodine under metal- and external oxidant-free reaction conditions has been developed. A variety of (E)-2-styrylazaheterocycles have been produced in moderate to excellent yields. The mechanistic exploration indicated that the N-oxide group played dual roles as both the directing group and an internal oxidant in this catalytic cycle.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Application In Synthesis of 8-Hydroxyquinoline 1-oxide. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about A new non-metal heterogeneous catalyst for the activation of hydrogen peroxide: a perfluorinated ketone attached to silica for oxidation of aromatic amines and alkenes. Author is Neimann, Karine; Neumann, Ronny.

A silane functionalized by octafluoroacetophenone was polymerized by the sol-gel method to form an insoluble silicate with perfluoroketone pendants; the silicate was used as a heterogeneous catalyst for the activation of aqueous hydrogen peroxide and the oxidation of aromatic amines and alkenes.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Electric Literature of C9H7NO2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about Structures of pyridine and quinoline-N-oxide. Author is Desiderato, Robert; Terry, J. C..

8-Hydroxyquinoline 1-oxide (I) and 2-(hydroxymethyl)pyridine 1-oxide (II) exhibited lengthened N-O bond distances (1.333 and 1.332 Å) due to delocalization of the nonbonding electron on the O as a result of H bonding. The H bond between the hydroxyl H and the dative O is intramol. (1.42 Å long) in I and intermol. in II (1.99 Å long). The pyridine and quinoline moieties are planar. Crystals have monoclinic symmetry, space group P21/c, and Z = 4. Compound, lattice constants a, b, c, and cos. β are: I, 12.136, 4.921, 13.138 Å, -0.3376; II, 7.079, 8.046, 10.599 Å, -0.2254.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1127-45-3, is researched, SMILESS is OC1=CC=CC2=CC=C[N+]([O-])=C12, Molecular C9H7NO2Journal, Guijinshu called Synthesis of gold(III) and palladium(II) complexes with 8-quinolinol-N-oxide and 5,7-dinitro-8-quinolinol-N-oxide, Author is Gong, Yuqiu; Jiang, Meichun, the main research direction is hydrogen bond quinolinol oxide proton chloroaurate; palladium quinolinol oxide complex.HPLC of Formula: 1127-45-3.

(HL2)[AuCl4] (L = 8-quinolinol N-oxide), [PdL2].0.85H2O, PdL’2 (L’ = 5,7-dinitro-8-quinolinol N-oxide), and [PdL’2].3NH3 were prepared Their compositions and properties have been determined by elemental anal., IR, UV, H-NMR and fluorescence spectra, molar conductance and x-ray powder diffraction. Their mol. structures are discussed too. These complexes can be classified as two types. One is the ion-associated compound containing a hydrogen bond. The other is the six-membered metal chelates containing metal-oxygen bonds.

If you want to learn more about this compound(8-Hydroxyquinoline 1-oxide)HPLC of Formula: 1127-45-3, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1127-45-3).

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Application In Synthesis of 8-Hydroxyquinoline 1-oxide. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about Complexation of dimethyltin(IV) ion with 2-mercaptopyridine N-oxide and 8-hydroxyquinoline N-oxide. Author is Singh, K. Ajit; Gupta, V. D..

Thermodn. parameters were determined for the complexation of Me2SnCl2 with the title N-oxides. In both cases ΔG and ΔH were neg.; ΔS was neg. for complexation with 2-mercaptopyridine N-oxide and pos. for complexation with 8-hydroxyquinoline N-oxide.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider