Category: 1448-87-9

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Synthesis of Cyano-Substituted Heterocycles by Means of Tetraethylammonium Cyanide

Chloropyrimidines 2, 3 and Chlorquinazolines 9, 10, after conversion into trimethylammonio derivatives 4, 5, 11, 12, react with tetraethylammonium cyanide 1a under very mild conditions to give pyrimidine carbonitriles 6, 7 and quinazoline carbonitriles 13, 14.Direct synthesis of quinoxaline carbonitriles 19 is possible by reaction of chloroquinoxalines 15, 18 with 1a.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N595 | ChemSpider

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 1448-87-9, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1448-87-9, Name is 2-Chloroquinoxaline, molecular formula is C8H5ClN2

Visible-light mediated carbamoyl radical addition to heteroarenes

The generation of carbamoyl radicals, followed by their addition to heteroarenes, was performed under mild conditions through a metal-free photocatalyzed decarboxylation of oxamic acids. The process has been applied to the carbamoylation of heteroaromatic bases using alpha-aminoacid-derived oxamic acids, leading to the corresponding amides without racemization.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N602 | ChemSpider

Reference of 1448-87-9, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1448-87-9, Name is 2-Chloroquinoxaline, molecular formula is C8H5ClN2. In a Patent£¬once mentioned of 1448-87-9

CERTAIN IMIDAZOQUINOXALINONES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS

This invention encompasses compounds of the formula: STR1 and the pharmaceutically acceptable non-toxic salts thereof wherein R 1, R. sub.2, R 3, R 4 are variables;

X and Y represent hydrogen, halogen, hydroxy or amino substituents, with the proviso that when Y is a hydrogen, halogen, or amino substituent, X is hydroxy; and< P>

W represent aryl groups unsubstituted or substituted with halogen, hydroxy, alkyl, alkoxy or amino groups.

These compounds or prodrugs thereof are highly selective agonists, antagonists or inverse agonists or GaBAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorder, overdose with benzodiazepine drugs, and enchancement of memory.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N487 | ChemSpider

Electric Literature of 1448-87-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 1448-87-9, 2-Chloroquinoxaline, introducing its new discovery.

Process for preparation of benzo[f]quinolinones

A series of benzoquinolin-3-ones are pharmaceuticals effective in treating conditions consequent on both Type I and Type II 5alpha-reductase and their preparation is disclosed.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 1448-87-9. In my other articles, you can also check out more blogs about 1448-87-9

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N464 | ChemSpider

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of 2-Chloroquinoxaline, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1448-87-9, Name is 2-Chloroquinoxaline, molecular formula is C8H5ClN2

Dialkylaminoacetonitrile Derivatives as Amide Synthons. A One-Pot Preparation of Heteroaryl Amides via a Strategy of Sequential SNAr Substitution and Oxidation

Dialkylamino acetonitrile derivatives were utilized as alternative to cyanohydrin synthons for preparation of the corresponding heteroaryl dialkyl amides via a strategy of sequential base-mediated coupling and oxidation. The most advantageous oxidant, NiO2-H2O, can readily oxidize 2-substituted aminoacetonitriles to the corresponding amides under both basic and neutral conditions by forming cyanohydrins in situ.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N736 | ChemSpider

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Safety of 2-Chloroquinoxaline, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 1448-87-9, name is 2-Chloroquinoxaline. In an article£¬Which mentioned a new discovery about 1448-87-9

Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme

The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.

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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N495 | ChemSpider

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. name: 2-Chloroquinoxaline. Introducing a new discovery about 1448-87-9, Name is 2-Chloroquinoxaline

Preparation of derivatives of 1-(2-pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents

(Chemical Equation Presented) This paper describes the preparation of twenty-eight derivatives of 1-(2-pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents. In twenty-six of the preparations a chloro nitrogen heterocycle was caused to react with an excess of 1-(2-pyrimidinyl)piperazine in the absence of solvent. A specific example is given above.

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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N525 | ChemSpider

Reference of 1448-87-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 1448-87-9, 2-Chloroquinoxaline, introducing its new discovery.

Inhibitors of cholesteryl ester transfer protein

This invention relates to inhibitors of CETP and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders mediated by CETP.

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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N477 | ChemSpider

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C8H5ClN2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1448-87-9, Name is 2-Chloroquinoxaline, molecular formula is C8H5ClN2

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N502 | ChemSpider

Reference of 1448-87-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1448-87-9, Name is 2-Chloroquinoxaline, molecular formula is C8H5ClN2. In a Article£¬once mentioned of 1448-87-9

(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: Synthesis, in vitro, in vivo, and X-ray crystallographic characterization

A series of pyrrolidine based inhibitors of dipeptidyl peptidase IV were developed from a high throughput screening hit for the treatment of type 2 diabetes. Potency, selectivity, and pharmacokinetic properties were optimized resulting in the identification of a pre-clinical candidate for further profiling.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N720 | ChemSpider