Category: 17056-99-4

New Advances in Chemical Research, May 2021. In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Synthetic Route of 17056-99-4, We’ll be discussing some of the latest developments in chemical about CAS: 17056-99-4, name is Quinoxalin-5-ol. In an article，Which mentioned a new discovery about 17056-99-4

There is interest in developing potent, selective, and cell-permeable inhibitors of human ferrous iron and 2-oxoglutarate (2OG) oxygenases for use in functional and target validation studies. The 3-component Betti reaction enables efficient one-step C-7 functionalisation of modified 8-hydroxyquinolines (8HQs) to produce cell-active inhibitors of KDM4 histone demethylases and other 2OG oxygenases; the work exemplifies how a template-based metallo-enzyme inhibitor approach can be used to give biologically active compounds.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N116 | ChemSpider

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Compounds of the general formula (I):wherein the variables are as defined in the specification are useful for the prophylaxis or treatment of serotonin-related, especially 5-HT 2 receptor-related, diseases in human beings or animals, particularly diseases related to the 5-HT2 c receptor, especially diseases such as eating disorders, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctionions, and urinary disorders.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N104 | ChemSpider

Reference of 17056-99-4, New Advances in Chemical Research in 2021. Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.17056-99-4, Name is Quinoxalin-5-ol, molecular formula is C8H6N2O. In a article，once mentioned of 17056-99-4

The synthesis and structure-activity relationship of a series of novel gp120-CD4 inhibitors are described. Pharmacokinetic studies and antiviral spectrum assessment of lead compounds led to the identification of compound 36, a potent gp120-CD4 inhibitor which exhibited antiviral potency across a spectrum of 25 clade B isolates.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N117 | ChemSpider

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A high throughput screening approach to the identification of selective cholecystokinin-2 receptor (CCK-2R) ligands resulted in the discovery of a novel series of antagonists, represented by 1-[2-[(2,1,3-benzothiadiazol-4- ylsulfonyl)amino]-5-chlorobenzoyl]-piperidine (1; CCK-2R, pKI = 6.4). Preliminary exploration of the structure-activity relationships around the anthranilic ring and the amide and sulfonamide moieties led to a nearly 50-fold improvement of receptor affinity and showed a greater than 1000-fold selectivity over the related cholecystokinin-1 receptor. Pharmacokinetic evaluation led to the identification of 4-[4-iodo-2-[(5-quinoxalinylsulfonyl)amino]benzoyl]- morpholine, 26d, a compound that demonstrates promising pharmacokinetic properties in the rat and dog with respect to plasma clearance and oral bioavailability and is a potent inhibitor in vivo of pentagastrin-stimulated acid secretion in the rat when dosed orally.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N108 | ChemSpider

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. Formula: C8H6N2O, In a article, mentioned the application of 17056-99-4, Name is Quinoxalin-5-ol, molecular formula is C8H6N2O

Quinoid inhibitors of Cdc25B were designed based on the Linear Combination of Atomic Potentials (LCAP) methodology. In contrast to a published hypothesis, the biological activities and hydrogen peroxide generation in reducing media of three synthetic models did not correlate with the quinone half-wave potential, E1/2.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N114 | ChemSpider

New Advances in Chemical Research, May 2021. The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. Synthetic Route of 17056-99-4, We’ll be discussing some of the latest developments in chemical about CAS: 17056-99-4, name is Quinoxalin-5-ol. In an article，Which mentioned a new discovery about 17056-99-4

The present invention relates to chinoxaline compounds, to the use thereof, to an organic semiconductor material, to an organic light-emitting diode, to an organic thin-layer transistor, or to an organic solar cell, and to the use of such an organic semiconductor material in an electronic, optoelectronic, or electroluminescent component for increasing the long-term stability and/or improving the short-circuit strength, a pn transition, and the use of a pn transition in an electronic, optoelectronic, or electroluminescent compound.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N107 | ChemSpider

New Advances in Chemical Research, May 2021. In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. Related Products of 17056-99-4, In a article, mentioned the application of 17056-99-4, Name is Quinoxalin-5-ol, molecular formula is C8H6N2O

The invention aims to allow a curable composition to have an extended working phase followed by a short time period in which said compound becomes fully cured. This is achieved by the provision of a curable composition comprising the following components: a) at least one polyether and/or at least one polyacrylic acid ester with at least one reactive silyl group as an end-group; b) at least one organotin compound; and c) at least one compound that does not contain any tin or silicon atoms and that has at least two functional groups. Said groups are selected from the following: carboxy, carbonyl or hydroxy groups, or nitrogen atoms that are part of a ring system with aromatic character. In addition, the invention relates to a method for producing such a composition, and to the use thereof as an adhesive, a sealant or as a coating material.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N105 | ChemSpider

New Advances in Chemical Research, May 2021. In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. Related Products of 17056-99-4, In a article, mentioned the application of 17056-99-4, Name is Quinoxalin-5-ol, molecular formula is C8H6N2O

The invention aims to allow a curable composition to have an extended working phase followed by a short time period in which said compound becomes fully cured. This is achieved by the provision of a curable composition comprising the following components: a) at least one polyether and/or at least one polyacrylic acid ester with at least one reactive silyl group as an end-group; b) at least one organotin compound; and c) at least one compound that does not contain any tin or silicon atoms and that has at least two functional groups. Said groups are selected from the following: carboxy, carbonyl or hydroxy groups, or nitrogen atoms that are part of a ring system with aromatic character. In addition, the invention relates to a method for producing such a composition, and to the use thereof as an adhesive, a sealant or as a coating material.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N105 | ChemSpider

Electric Literature of 17056-99-4, New Advances in Chemical Research in 2021. Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.17056-99-4, Name is Quinoxalin-5-ol, molecular formula is C8H6N2O. In a article，once mentioned of 17056-99-4

Biotransformation of quinoline, isoquinoline, quinoxaline and quinazoline using growing cultures of Pseudomonas putida UV4 yielded cis-dihydro diols from the oxidation of the carbocyclic aromatic ring.Aromatic hydroxylation was observed in both carbocyclic and heterocyclic rings.Ring cleavage of the quinoline skeleton to yield anthranilic acid, and cis-diol formation (with alkene bond reduction) to yield cis-5,6,7,8-tetrahydroquinazoline-5,6-diol from quinazoline were observed.The cis-dihydro diol metabolites of quinoline (5,6- and 7,8-) and quinoxaline (5,6-) were found to be optically pure, while metabolism of isoquinoline gave on e homochiral (5,6-) and one racemic 7,8-) cis-dihydro diol product.The absolute configuration of the cis-dihydro diol metabolites have been determined using 1H NMR analyses, stereochemical correlations and X-ray crystallography methods.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N110 | ChemSpider

New Advances in Chemical Research, May 2021. The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing theoretical assessments of solvent structures and their interactions with reaction intermediates. COA of Formula: C8H6N2O, We’ll be discussing some of the latest developments in chemical about CAS: 17056-99-4, name is Quinoxalin-5-ol. In an article，Which mentioned a new discovery about 17056-99-4

Novel heterocyclic compounds, which are represented by the following general formula, useful as anticancer drug potentiaters having a potentiating effect on the incorporation of anticancer drugs into cancer cells, the compounds each synthesized by, for example, reacting a epoxy compound obtained by reacting a heterocyclic compound with an epihalogenohydrin, with an amine derivative.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N106 | ChemSpider