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We describe here a simple method for the synthesis of 6-arylselanylpurines with antioxidant and anticholinesterase activities, and memory improvement effect. This class of compounds was synthesized in good yields by a reaction of 6-chloropurine with diaryl diselenides using NaBH4 as reducing agent and PEG-400 as solvent. Furthermore, the synthesized compounds were evaluated for their in vitro antioxidant and acetylcholinesterase (AChE) inhibitor activities. The best AChE inhibitor was assessed on the in vivo memory improvement. Our results demonstrated that the 6-((4-chlorophenyl)selanyl)-9H-purine and 6-(p-tolylselanyl)-9H-purine presented in vitro antioxidant effect. In addition, 6-((4-fluorophenyl)selanyl)-9H-purine inhibited the AChE activity and improved memory, being a promising therapeutic agent for the treatment of Alzheimer’s disease.

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The halogenation of pyridinium N-(benzoazynyl) aminides with N-halosuccinimides provides a mild and regioselective method to functionalize the negatively charged diazine moiety in most cases. In some examples, however, formation of other products is explained. Finally, alkylation of the exocyclic nitrogen and reduction of the N?N bond provides a simple and straightforward strategy to obtain functionalized N-benzyl-benzoazynyl-alpha-amines.

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Quinoxaline – Wikipedia,
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Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 18671-97-1. In my other articles, you can also check out more blogs about 18671-97-1

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The first syntheses of 4-chloro-2-(2-quinoxalinyl)-pyridazin-3(2H)-one derivatives are reported.They could be synthesized from 2-hydrazinoquinoxaline derivatives as starting materials.

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The invention discloses tetrahydroisoquinoline – 2 – base aryloxy phenoxy alkyl ketone compound and its application, the chemical structural formula shown in formula I or II: In the formula, R1 , R2 , R3 , R4 Are independently hydrogen or C1 – C3 C alkyl or1 – C3 Halogenated alkyl in any one of; X is nitrogen or carbon; X1 , X2 , X3 , X4 , X5 Are respectively hydrogen either fluorine or chlorine either bromine or iodine or trifluoromethyl or cyano or nitro in any one of the. The invention also relates to a composition containing the above-mentioned compound and tetrahydroisoquinoline – 2 – base aryloxy phenoxy cyclic amine in agricultural herbicide application, some compounds have herbicidal activity of very high, in the amount of 5 g/mu can be obtained under a very good control effect. (by machine translation)

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Reference of 18671-97-1, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.18671-97-1, Name is 2,6-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a article,once mentioned of 18671-97-1

[Problem] new ketone or oxime compound, containing the chemicals, in particular of the herbicide. (1) A compound of the formula [a]. [In the formula, a represents B B-a 1 or B-a 2, Q is an oxygen atom or NOR7 Represents a, represents a hydrogen atom or the like is A, R6 C is1 – C6 Alkyl represents e.g., R7 C is1 – C6 Alkyl represents e.g., R8A And R9A C represents hydrogen atom or1 – C6 Represents an alkoxycarbonyl, R8B And R9B Represents a hydrogen atom, Z4 C is1 – C6 Alkyl represents e.g., Z7 The a-OR41 Represents a, R41 The D3 – 18a of the heterocycle. ] Ketone or oxime compound expressed herbicide containing them. [Drawing] no (by machine translation)

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 18671-97-1, name is 2,6-Dichloroquinoxaline, introducing its new discovery. category: quinoxaline

An efficient synthesis of (R)-(+)-2-[4-(6-chloro-2-quinoxalinyloxy)- phenoxy]-propion-amide 4a-e is described by simple amidation of Quizalofop-methyl [(R)-(+)-3]. The reduced susceptibility of quinoxalinyl moiety of (R)-(+)-3 toward nucleophilic reagents was discussed on the basis of QM calculation.

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Compounds of Formula (I), wherein the substituents are as defined in claim 1, are suitable for use as herbicides.

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Compounds of Formula I: (I) in which A, A1, R1, R7a, R7b, R8 and R10 have the meanings given in the specification, are DP2 receptor inhibitors useful in the treatment and prevention of immunologic diseases, allergic diseases such as asthma, allergic rhinitis and atopic dermatitis, and other inflammatory diseases mediated by prostaglandin D2 (PGD2). The compounds of Formula I may also be useful in treating diseases or medical conditions involving the Th2 T cell via production of IL-4, IL-5 and/or IL- 13

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 18671-97-1, name is 2,6-Dichloroquinoxaline, introducing its new discovery. Product Details of 18671-97-1

The herbicidal activity of a set of N-methyl arylaminophenoxypropionate esters 3 has been compared to the analogous aryloxyphenoxypropionates 1. The usefulness of N-methyl as a novel bioisostere for ether links is shown by the surprisingly high herbicidal activity of the 6-chloroquinazolin-2-yl- and 7-chloro-1,2,4-benzotriazin-3-yl-N-methylamino- phenoxypropionate esters 3h and 3i.

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, category: quinoxaline, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 18671-97-1, Name is 2,6-Dichloroquinoxaline, molecular formula is C8H4Cl2N2

The invention discloses fragrant oxygen benzene oxygen acid derivatives and their herbicidal activity, the chemical structural formula shown in formula I or II: In the formula, R1 C is hydrogen or1 – C3 C alkyl or1 – C3 Halogenated alkyl in any one of; X is nitrogen or carbon; X1 , X2 , X3 For hydrogen either fluorine or chlorine either bromine or iodine or trifluoromethyl or cyano or nitro in any one of the. The invention also relates to a composition containing the above-mentioned compound and fragrant oxygen benzene oxygen acid derivatives in agricultural herbicide application, some compounds have herbicidal activity of very high, in the amount of 5 g/mu can be obtained under a very good control effect. (by machine translation)

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. category: quinoxaline, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 18671-97-1, in my other articles.

Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1626 | ChemSpider