Category: 2213-63-0

Related Products of 2213-63-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a article£¬once mentioned of 2213-63-0

A novel tandem cyclization of condensed 2,3-dialkynylpyrazines into [1,2,3]triazolo[1?,5?;1,2]pyrido[3,4-b]pyrazines promoted by sodium azide

6,7-Dialkynyl-1,3-dimethylpteridine-2,4(1H,3H)-diones and 2,3-dialkynylquinoxalines have been shown to react with sodium azide in DMF at room temperature giving rise 9,11-dimethyl-[1,2,3]triazolo[1?,5?;1,2]pyrido[4,3-g]pteridine-8,10(9H,11H)-diones and [1,2,3]triazolo[1?,5?;1,2]pyrido[3,4-b]quinoxalines. A novel tandem cyclization involves 1,3-dipolar cycloaddition of an azide ion to the carbon-carbon triple bond followed by intramolecular nucleophilic addition of the intermediate 1,2,3-triazole N-anion to another C{triple bond, long}C bond.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1345 | ChemSpider

2213-63-0, Name is 2,3-Dichloroquinoxaline, belongs to quinoxaline compound, is a common compound. category: quinoxalineIn an article, once mentioned the new application about 2213-63-0.

Part I: Synthesis, cancer chemopreventive activity and molecular docking study of novel quinoxaline derivatives

The reaction of o-phenylene diamine and ethyl oxamate is reinvestigated and led to 3-aminoquinoxalin-2(1H)-one rather than benzimidazole-2-carboxamide as was previously reported. The structure of the obtained quinoxaline has been confirmed by X-ray. The anti-tumor activity of synthesized quinoxalines 1-21 has been evaluated by studying their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13- acetate (TPA). Among the studied compounds 1-21, compounds 12, 8, 13, 18, 17 and 19, respectively, demonstrated strong inhibitory effects on the EBV-EA activation without showing any cytotoxicity and their effects being stronger than that of a representative control, oleanolic acid. Furthermore, compound 12 exhibited a remarkable inhibitory effect on skin tumor promotion in an in vivo two-stage mouse skin carcinogenesis test using 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter. The result of the present investigation indicated that compound 12 might be valuable as a potent cancer chemopreventive agent. Moreover, the molecular docking into PTK (PDB: 1t46) has been done for lead optimization of the aforementioned compounds as potential PTK inhibitors.

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Synthetic Route of 2213-63-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 2213-63-0, molcular formula is C8H4Cl2N2, introducing its new discovery.

Synthesis and photochemical reaction of novel, visible-wavelength oxidizable polymerization sensitizer based on the 12H-quinoxalino[2,3-b][1,4]benzothiazine skeleton

Novel dyes based on the 12H-quinoxalino[2,3-b] [1,4]benzothiazine skeleton were synthesized and subsequently characterized using 1H NMR. Their electrochemical and spectral properties, such as absorption and emission spectra, quantum yield of fluorescence, and quantum yield of singlet oxygen formation, were measured. These compounds were evaluated as sensitizers for alkoxypyridinium salt photodecomposition, and the results are discussed on the basis of the free energy change for electron transfer from benzothiazine dyes to alkoxypyridinium compounds. Benzothiazine dyes are useful oxidizable sensitizers for N-alkoxypyridinium photoinitiators. The mechanism of the dye photobleaching is supported by time-dependent density functional theory (TD-DFT) calculations and the quantum yields of sensitized proton formation. Photoredox pairs consisting of benzothiazine dyes and alkoxypyridinium salt were found to be effective initiation systems for free radical polymerization of methyl acrylate and trimethylolpropane triacrylate (TMPTA) using visible light.

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Quinoxaline | C8H6N1503 | ChemSpider

Electric Literature of 2213-63-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a Article£¬once mentioned of 2213-63-0

Metal catalyst free cyclization of 3-alkynyl substituted 2-(indol-3-yl)quinoxalines in TFA alone: a new synthesis of indolophenazines

TFA alone was found to be remarkably effective for the intramolecular hydroarylation (IMHA) of alkynes when employed as a solvent in the cyclization of 3-alkynyl substituted 2-(indol-3-yl)quinoxalines. This simple and metal free cyclization method afforded a range of indolophenazines as new and potential cytotoxic agents. The use of excess TFA was found to be crucial for the success of this reaction.

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Quinoxaline | C8H6N1414 | ChemSpider

Application of 2213-63-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a Article£¬once mentioned of 2213-63-0

2-(4,5-Dihydro-1H-imidazol-2-yl)thiophenol and Analogous Compounds as Building Blocks in the Synthesis of Heterocycles.

2-(4,5-Dihydro-1H-imidazol-2-yl)thiophenol (1) and analogous compounds react with biselectrophiles under ring closure to give doubly (or more) annulated heterocyclic systems containing six- or seven-membered rings.

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Quinoxaline | C8H6N1518 | ChemSpider

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 2213-63-0, name is 2,3-Dichloroquinoxaline, introducing its new discovery. Recommanded Product: 2213-63-0

Reactions of 5-Mercapto-3-(4′-pyridyl)-s-triazole with alpha-Halogenoketones, 1,2-Dibromoethane and 2,3-Dichloroquinoxaline: Synthesis of Thiazolo<2,3-c>-s-triazoles and s-Triazolo<3',4':2,3>thiazolo<4,5-b>quinoxaline

5-Mercapto-3-(4′-pyridyl)-s-triazole (I; R = 4-pyridyl) reacts with alpha-halogenoketones to give 5-aroylmethylthio-3-(4′-pyridyl)-s-triazoles (IIa-f) which on treatment with PPA undergo cyclodehydration to furnish 5-aryl-3-(4′-pyridyl)thiazolo<2,3-c>-s-triazoles (IIIa-f) and not the isomeric 5-aryl-2-(4′-pyridyl)thiazolo<3,2-b>-s-triazoles (VIIIa-f).The structural assignments of III are based on elemental analyses, spectral data and the unequivocal synthesis of IIIa (R = 4-pyridyl; R1 = p-ClC6H4) by POCl3 cyclization of 4-(p-chlorophenyl)-2-isonicotinylhydrazinothiazole (V) obtained from isonicotinyl thiosemicarbazide (IV) and p-chlorophenacyl bromide.A similar condensation of I (R = 4-pyridyl) with 1,2-dibromoethane yields 5,6-dihydro-3-(4′-pyridyl)thiazolo<2,3-c>-s-triazole (VI) and not its isomer, 5,6-dihydro-2-(4′-pyridyl)thiazolo<3,2-b>-s-triazole (IX).This has also been proved by the unequivocal synthesis of VI by the reaction of IV with 1,2-dibromoethane.The reaction of I (R = 4-pyridyl) with 2,3-dichloroquinoxaline gives 3-(4′-pyridyl)-s-triazolo<3',4':2,3>thiazolo<4,5-b>quinoxaline (VII).

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Quinoxaline | C8H6N1376 | ChemSpider

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 2213-63-0, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2

Heteroaromatic motifs in resorcinarene-derived cavitand receptors: Structural and functional elements

Cavitands are synthetic receptors typically based on resorcin[4]arenes, macrocyclic concave compounds that are readily available and can be easily transformed into deeper synthetic cavities by attachment of aromatic spacers or panels. The use of aromatic heterocycles is ubiquitous in these structures, either for synthetic convenience, to regulate the dynamic and self-assembling properties of these receptors, or to provide suitable coordination environments for metal-functionalized receptors.

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Safety of 2,3-Dichloroquinoxaline, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 2213-63-0, name is 2,3-Dichloroquinoxaline. In an article£¬Which mentioned a new discovery about 2213-63-0

Synthesis and spectral studies of sterically hindered half-sandwich d6 metal complexes containing quinoxaline based electron rich heterocyclic pyrazoles

Reactions of halide bridged arene d6 metal precursors with the quinoxaline based electron rich heterocyclic (furan or thiophene) pyrazoles (L1-L4) yielded a series of mononuclear complexes 1?16. In general complexes have been formulated as [(arene)MClL]PF6 where L = L1, M = Ru, arene = benzene (1); p-cymene (2); arene = Cp?, M = Rh (3) and Ir (4); L = L2, M = Ru, arene = benzene (5); p-cymene (6); arene = Cp?, M = Rh (7) and Ir (8); L = L3, M = Ru, arene = benzene (9); p-cymene (10); arene = Cp?, M = Rh (11) and Ir (12); L = L4, M = Ru, arene = benzene (13); p-cymene (14); arene = Cp?, M = Rh (15) and Ir (16). All these cationic complexes have been characterized by various spectroscopic techniques. Most of the complexes (except 3, 11, 15 and 16) have been established by single crystal analysis. Structural studies revealed that complexes are mononuclear and X-ray studies suggest that the vicinity around the metal atom is distorted octahedral. Variation in the heterocyclic moiety of the ligands doesn’t influence in the mode of bonding towards the metal atoms in the complexes. Moreover, the molar ratio between the metal precursors and ligands, effect of temperature and the reaction times does not influence the elucidation of the di-nuclear complexes.

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Related Products of 2213-63-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a Article£¬once mentioned of 2213-63-0

A new efficient route for the formation of quinoxaline N-oxides and N,N?-dioxides using HOF¡¤CH3CN

HOF¡¤CH3CN, a very efficient oxygen-transfer agent made readily from fluorine and aqueous acetonitrile, was reacted with various quinoxaline derivatives to give the corresponding mono N-oxides and especially the N,N?-dioxides in very good yields under mild conditions and short reaction times.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 2213-63-0. In my other articles, you can also check out more blogs about 2213-63-0

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1287 | ChemSpider

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 2213-63-0, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2

Synthesis and antimicrobial activity of chromone-linked 2-pyridone fused with 1,2,4-triazoles, 1,2,4-triazines and 1,2,4-triazepines ring systems

Three series of novel fused nitrogen heterocyclic systems such as 1,2,4-triazolo[1,5-a] pyridines (5-7 and 9), pyrido[1,2-b][1,2,4]triazines (10, 11, 13 and 15), and pyrido[1,2-b][1,2,4]triazepines (17, 18, 20 and 22) linked with a chromone moiety were synthesized from the key intermediate 1,6-diamino-(6-chloro-4-oxo-4H-chromen-3-yl)-2-oxo-1,2-dihydropyridine-3, 5-dicarbonitrile (4) with some electrophilic reagents. The structures of the novel compounds were established by elemental analyses and spectral data. All the products were also screened in vitro for their antimicrobial activity. Compounds 7, 9 and 15 showed the highest activities when compared with the reference drugs.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1248 | ChemSpider