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Reference of 2213-63-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a article£¬once mentioned of 2213-63-0

Some Sulfur-containing Quinoxalines (1)

A series of quinoxalines having oxygen, chlorine or sulfur substituted at the 2-position and long-chain alkyl, alkylthio, arylthio, alkylthioalkyl or arylthioalkyl groups at the 3-position have been synthesized.

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A One-pot Facile Synthesis of 2,3-Dihydroxyquinoxaline and 2,3-Dichloroquinoxaline Derivatives Using Silica Gel as an Efficient Catalyst

An efficient one-pot reaction has been developed for the synthesis of 2,3-dichloroquinoxaline derivatives 3a?n. The reaction was performed in two steps via a silica gel catalyzed tandem process from o-phenylenediamine and oxalic acid, followed by addition of phosphorus oxychloride (POCl3). A variety of 2,3-dichloroquinoxalines have been obtained in good to excellent overall yields. Eight known compounds 3a?3h were characterized by IR, 1H-NMR, and mass spectroscopies. Compounds 3i?3n without spectroscopic data were characterized by IR, 1H-NMR, 13C-NMR, and mass spectroscopies.

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Studies in the Heterocyclic Series.XIX.Synthesis of 1,4-diazaphenothiazine and its Benzo Derivatives

1,4-Diazaphenothiazine, the parent compound of this heterocyclic ring has now been prepared from 2,3-dichloropyrazine and 2-aminothiophenol.Replacement of 2,3-dichloropyrazine with 2,3-dichloroquinoxaline and 2,3,6-trichloroquinoxaline led to the corresponding 1,4-diazabenzophenothiazine in good yields.Structural assignments were made by spectroscopic studies and by certain chemical transformations.

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Condensed bridgehead nitrogen heterocyclic systems: Microwave assisted synthesis and bioactivity of s-triazolo[3,4-b][1,3,4]thiadiazoles, s-triazolo[3,4-b][1,3,4]thiadiazines and s-triazolo [3?,4?:2,3]- thiadiazino[5,6-b]quinoxaline

N-[3-(4-Amino-5-mercapto-4H-[1,2,3]triazol-3-yl)-4,5,6,7-tetrahydrobenzo[b] thiophen-2-yl]acetamide 1 on condensation with chloroacetic acid, alpha-haloketone and benzoin furnishes [1,2,4]triazolo[3,4-b][1,3,4] thiadiazine derivatives 2, 3 and 4 respectively, while condensation with 2,3-dichloroquinoxaline, carbon disulphide, aromatic carboxylic acid and aromatic carboxaldehydes yield the cyclic products, [1,2,4] triazolo[3,4-b][1,3, 4]thiadiazole derivatives 5, 6, 7, 8 respectively. The compounds have been characterized on the basis of elemental analysis and spectral data. The antibacterial, antifungal and antitubercular activities of the compounds have also been evaluated.

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Final Thoughts on Chemistry for 2,3-Dichloroquinoxaline

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Synthesis, characterization, and optical properties of new metal complexes with the multi-sulfur 1,2-dithiolene ligand

Metal complexes containing a new multi-sulfur atom containing 1,2-dithiolene ligand, [4?,5?:5,6] [1,4] dithiino[2,3-b] quinoxaline-1?,3?-dithiolate, have been synthesized and characterized by electrochemical measurements, IR, UV-NIR and ESR spectroscopies. X-ray structure analysis reveals that the anions of the Ni-complex derived from the new ligand form a zig-zag chain along the b axis, and the anions of Au complex of the ligand stack along the a axis while the cations occupy the holes. The Ni-complex exhibits remarkable absorption at 1082 nm (epsilon = 15 000 dm3 mol-1 cm-1) and good solubility that render this complex as a promising near-IR dye for Q-switching neodymium lasers. The third-order non-linear optical properties of the complexes are measured by the Z-scan technique with a 6.5 ns pulsed laser at 532 nm. The Au complexes exhibit non-linear optical absorptive abilities, while the non-linear absorption of the nickel complex is negligible. All of the complexes show effective self-defocusing performance. The third-order non-linear optical susceptibilities for the Au complexes have been determined to be of the order of 10-13 esu.

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Extracurricular laboratory:new discovery of 2,3-Dichloroquinoxaline

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Bridgehead nitrogen heterocyclic systems: Synthesis and antimicrobial activity of s-triazolo[3,4-b][1,3,4]thiadiazoles, 5-triazolo[3,4-b][1,3,4]thiadiazines and s-triazolo[3?,4?:2,3]-thiadiazino[5,6-b]quinoxaline

The condensation of 3-n-propyl-4-amino-5-mercapto-5- triazolo 1 with chloroacetic acid, alpha-haloketone, benzoin, bromoacetaldehyde diethyl acetal, 2,3-dichloroquinoxaline, carbon disulphide, aromatic carboxylic acids and aromatic carboxaldehydes furnished in one-step the cyclic products, 3-n-propyl7H-s-triazolo[3,4-b][1,3,4]thiadiazin-6(5H)-one 2, 6-aryl-3-n-propyl-7H-5-triazolo[3,4-b)[1,3,4]thiadiazine 3, 3-n-propyl-6,7-diphenyl-5H-s-triazolo[3,4-b] [1,3,4]-thiadiazine 4, 3-n-propyl-7H-s-triaolo[3,4-b]-[1,3,4]thiadiazine hydrobromide 5, 3-n-propyl-5H-5-triazolo[3?,4?:2,3][1,3,4]thiadiazino[5,6-6] quinoxaline 6, 3-n-propyl-s-triazolo [3,4-6] [1,3,4] thiadiaole-6(5H)-thione 7, 3-n-propyl-6-aryl-5-triazolo [3,4-b] [1,3,4]thiadiazoles 8 and 6-aryl-5,6-dihydro-3n-propyl-.y-triazolo[3,4-&] [1,3,4]thiadiazoles 9 respectively, on the basis of elemental analysis and spectral data. The antibacterial and antifungal activity of some of the compound have also been evaluated.

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Novel bridgehead nitrogen heterocyclic systems: Synthesis and antimicrobial activity of imidazo[2,1-b]-1,3,4-thiadiazolo[2,3-c]-s-triazoles, s-triazolo[3,4-b] [1,3,4]thiadiazolo[3,2-b]imidazo[4,5-b]quinoxaline and bis-(s-triazolo[3,4b][1,3,4]thiadiazolo[3,2-b] [imidazo[4,5-b]-cyclohexane]-5a, 6a-diene)

Condensation of 4-amino-5-mercapto-3-p-(t-butylphenyl)-s-triazole 1 with cyanogen bromide gives 6-amino-3-p-(tbutylphenyl)-s-triazolo[3,4-b][1,3,4]thiadiazole 2 which on condensation of with chloranil yields 3,9-di-p-(t-butylphenyl)6,14-dioxo-bis-(s-triazolo[3,4-b] [1,3,4]thiadiazolo[3,2-b]-[imidazo[4,5-b]cyclohexane]-5a,6a-diene) 3. 3-p-(t-Butylphenyl)s-triazolo[3,4-b][1,3,4]thiadiazolo[3,2-b]-imidazo [4,5-b] quinoxaline 4 is obtained by a similar condensation of 2 with 2,3-dichloroquinoxaline. The reaction of 2 with alpha-haloketones followed by bromination affords 7-aryl-3-p-(t-butylphenyl)imidazo[2,1-b]-1,3,4-thiadiazolo[2,3-c]-s-triazoles 5 and their 6-bromo analogues 6 respectively. The antibacterial and anti-fungal activities of some of the compounds have also been evaluated.

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Syntheses, structures, and magnetic properties of heterobimetallic clusters with tricyanometalate and phi-Conjugated ligands containing 1, 3-dithiol-2-ylidene

Two new phi-conjugated 1, 3-dithiol-2-ylidene-containing ligands, 4, 5-[10, 40]dithiino[20, 30-b]quinoxaline-2-bis(2-pyridyl) methylene-1, 3-dithiole (L1) and 4, 5-bis(methylthio)-2-bis(2-pyridyl)methylene-1, 3-dithiole (L2), have been synthesized and characterized. Using L1, L2, or dimethyl 2-[di(pyridin-2-yl)methylene]-1, 3-dithiole-4, 5-dicarboxylate (L3) as the auxiliary ligand and [(Tp)Fe(CN)3]-or [(i-BuTp)Fe(CN)3]-[Tp = tris(pyrazolyl)borate; i-BuTp = 2-methylpropyltris(pyrazolyl)borate] as the building block, two rectangular-square Fe2Ni2 clusters [(Tp)Fe(CN)3-Ni(L1)2]2 ¡¤ 2ClO4 ¡¤ 6H2O (1) and [(i-BuTp)Fe(CN) 3Ni(L3)2]2 ¡¤ 2ClO4 ¡¤ 6H2O (2) and two trinuclear clusters [(Tp) 2Fe2(CN)6Ni(L2)2] ¡¤ 8H2O (3) and [(Tp)2Fe2(CN) 6Co(L3)2] ¡¤ 5H2O (4) have been prepared in parallel and structurally characterized. Complexes 1 and 2 show similar square structures, and weaker intermolecular phi-phi-stacking interactions through the pyrazolyl groups of the Tp-ligands are observed. 2D sheet structures are formed in complexes 3 and 4 through intermolecular phi-phi-stacking interactions. In 3, shorter S 3 3 3 S contacts further connect the 2D sheets to 3D supramolecular structures. Magnetic studies show intramolecular ferromagnetic coupling in complexes 1-4. Complexes 1 and 2 show obvious frequency dependencies in the alternating-current magnetic susceptibility data, indicating single-molecule-magnet behavior with effective spin-reversal barriers of 8.7 K for 1 and 13.5 K for 2, respectively.

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Utility of ethylidenethiosemicarbazides in heterocyclic synthesis

This review imparts a survey on the synthesis and reactions of ethylidenethiosemicarbazides as well as their biological activities during the period from 2005 to 2015. The synthetic utilities of ethylidenethiosemicarbazides, as building blocks, for the synthesis of various heterocyclic compounds such as azoles, azines, and fused ring systems, have been demonstrated.

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Phosphorylthioacetamides in the synthesis of annulated quinoxalines

Diethoxyphosphorylthioacetamide in the reaction with 2,3- dichloroquinoxaline acted as a thionating reagent, giving diethoxyphosphorylacetonitrile and 2-chloro-3-[(3-chloro-2-quinoxalinyl)thio] quinoxaline. Reactions of phosphorylthioacetamides with N-methylquinoxalinium iodide in alcohol media in the presence of a base proceeded stereoselectively to afford cis-3-phosphoryl-1,3,3a,4,9,9a-hexahydro-2H-pyrrolo[2,3-b]quinoxaline-2- thiones.

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