Category: 2379-60-4

2379-60-4, 2 3-Dichloro-6-nitroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A. 3-Chloro-2-hydrazino-6-nitroquinoxaline A mixture of 6.1 g (25 mmol) of 2,3-dichloro-6-nitroquinoxaline and 2.75 g (55 mmol) of hydrazine hydrate in 150 ml of ethanol was stirred at room temperature over night. The precipitate was isolated and washed with water, cold ethanol and ether to give 5.67 g (95%) of crude product., 2379-60-4

The synthetic route of 2379-60-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Novo Nordisk A/S; US5504085; (1996); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

2379-60-4, 2 3-Dichloro-6-nitroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

EXAMPLE 1 Preparation of 7-Nitro-1,4-dithiino(2,3-b)quinoxaline-2,3-dicarbonitrile To a solution of 2,3-dichloro-6-nitroquinoxaline (1.0 g, 0.0041 mol) in dimethylformamide (20 mL) is added, in several portions, disodium-Z-1,2-dicyano-1,2-ethylenedithiolate (1.1 g, 0.0045 mol). The resulting solution is stirred overnight at room temperature. Water (100 mL) is slowly added to the reaction mixture, dropwise, with stirring. The resulting solid is isolated by filtration, washed with water and dried, giving a dark purple powder. The recovered material weighs 0.92 g and has a melting point of 222 to 225 C. A calculated overall yield of 72 percent is achieved. The structure identity is confirmed by proton nuclear magnetic resonance spectroscopy (1 H), carbon nuclear magnetic resonance spectroscopy (NMR), infrared spectroscopy (IR) and mass spectrometry (MS).

2379-60-4, 2379-60-4 2 3-Dichloro-6-nitroquinoxaline 689090, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; The Dow Chemical Company; US5200409; (1993); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2379-60-4,2 3-Dichloro-6-nitroquinoxaline,as a common compound, the synthetic route is as follows.

2379-60-4, A. 3-Chloro-2-methoxy-6-nitroquinoxaline A slurry of 6.1 g (25 mmol) of 2,3-dichloro-6-nitroquinoxaline in 70 ml of dry methanol was heated to 50 C and treated dropwise over 5 h with 0.7 g (30 mmol) of sodium dissolved in 70 ml of dry methanol. The mixture was stirred over night at 50 C., cooled and filtered. The resulting precipitate was washed with cold ethanol and water and finally chromatographed on silica gel with toluene to give 3.5 g (58%) of the title compound; m.p. 155-158 C.; 1 H-NMR (DMSO-d6): delta4.17 (s, 3H, CH3), 8.05 (d,J=9 Hz, 1H, H-8), 8.48 (dd, J7-8 =9 Hz, J7-5 =2 Hz, 1H, H-7), 8.73 (d, J=2 Hz, 1H, H-5).

2379-60-4 2 3-Dichloro-6-nitroquinoxaline 689090, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; Novo Nordisk A/S; US5504085; (1996); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider