Category: 39267-04-4

New learning discoveries about 39267-04-4

39267-04-4, 39267-04-4 2,3-Dichloro-6-methoxyquinoxaline 684227, aquinoxaline compound, is more and more widely used in various fields.

39267-04-4, 2,3-Dichloro-6-methoxyquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

(a) Preparation of 2-chloro-3-hydrazino-6-methoxyquinoxaline 2,3-Dichloro-6-methoxyquinoxaline (4.2 g., 0.018 mole), the product of Preparation E(b), and 2.7 ml. of hydrazine hydrate in 100 ml. of ethanol were heated under reflux for 4 hours and stirred at room temperature overnight.

39267-04-4, 39267-04-4 2,3-Dichloro-6-methoxyquinoxaline 684227, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; Pfizer Inc.; US4495187; (1985); A;; ; Patent; Pfizer Inc.; US4547501; (1985); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

Simple exploration of 39267-04-4

The synthetic route of 39267-04-4 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.39267-04-4,2,3-Dichloro-6-methoxyquinoxaline,as a common compound, the synthetic route is as follows.

Example B 2,3-Dicyano-6-methoxyquinoxaline A mixture of 31.1 g of 2,3-dichloro-6-methoxyquinoxaline, 14.7 g of sodium cyanide and 2.79 g of benzyltrimethylammonium chloride is stirred in 210 ml of DMSO at room temperature for 48 hours. With intensive stirring the reaction mixture is poured onto 520 ml of ice-water, stirred for an hour, and filtered with suction, and the solid product is washed with water. Drying at 40 C. gives 23.8 g (83% of theory) of pale gray crystals with the following formula MS (m/e): 211 [M+H]+, 233 [M+Na]+ H NMR (DMSO): 8.21 (d, 1H), 7.83 (dd, 1H), 7.68 (d, 1H), 4.02 (s, 3H), 39267-04-4

The synthetic route of 39267-04-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Heckmann, Heino; Metz, Hans Joachim; US2007/264600; (2007); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

Brief introduction of 39267-04-4

As the paragraph descriping shows that 39267-04-4 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.39267-04-4,2,3-Dichloro-6-methoxyquinoxaline,as a common compound, the synthetic route is as follows.

39267-04-4, A mixture of 2,3-dichlorobenzenesulfonamide (0.5g) and cesium carbonate (0.72g) was stirred together for 10 minutes in 1-METHYL-2-PYRROLIDINONE (LOML) at rt. Then 2,3- dichloro-6-methoxyquinoxaline (0. Slg) was added and the resulting mixture heated to 100C for 24 hours. The reaction mixture was cooled and then acidified to pH 3 using 2M hydrocloric acid. The product was extracted with ethyl acetate (3x20mL). The combined extracts were dried over anyhdrous magnesium sulfate, filtered and concentrated to give the sub-titled compound as a yellow solid (0.62g).

As the paragraph descriping shows that 39267-04-4 is playing an increasingly important role.

Reference£º
Patent; ASTRAZENECA AB; WO2005/21513; (2005); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider