41959-35-7, 6-Nitro-1,2,3,4-tetrahydroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,41959-35-7
A mixture of 1 ,2,3,4-tetrahydro-6-nitro- quinoxaline (22.324 mmol), di-tert-butyl dicarbonate (22.324 mmol), triethylamine (44.648 mmol) and 4-dimethylaminopyridine (4.465 mmol) in DCM (40 ml) was stirred at room temperature for 2 hours. The reaction mixture was poured onto water and extracted with DCM. The organic layer was decanted, dried over MgSO4, filtered and evaporated to dryness. The residue (7.7g) was purified by HPLC (9Og SiO2 15/40 mum – eluent: DCM 100 to DCM/MeOH 99/1 ). The pure fractions were collected and evaporated to dryness, yielding 3.55g (57%) of intermediate 33.
The synthetic route of 41959-35-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; JANSSEN PHARMACEUTICA NV; WO2009/37343; (2009); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider