Category: 6924-66-9

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: Quinoxaline-5-carboxylic acid, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 6924-66-9, Name is Quinoxaline-5-carboxylic acid, molecular formula is C9H6N2O2

Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine

Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties and diverse therapeutic applications in medicinal research. They are complementary in shapes and charges to numerous biomolecules they interact with, thereby resulting in increased binding affinity. The pharmacokinetic properties of drugs bearing quinoxaline cores have shown them to be relatively easy to administer either as intramuscular solutions, oral capsules or rectal suppositories. This work deals with recent advances in the synthesis and pharmacological diversities of quinoxaline motifs which might pave ways for novel drugs development.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: Quinoxaline-5-carboxylic acid, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 6924-66-9, in my other articles.

Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N772 | ChemSpider

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6924-66-9,Quinoxaline-5-carboxylic acid,as a common compound, the synthetic route is as follows.

6924-66-9, To a solution of 8-amino-2-(2-chloro-4-fluorophenyl)-2-azaspiro[4.5]decan-1 -one (isomer 2 Intermediate 113), (75.0 mg, 253 mupiiotaomicronIota) in DMF (2.6 ml) was added PyBOP (145 mg, 278 muiotaetaomicronIota), N,N-diisopropylethylamine (180 muIota, 1.0 mmol) and quinoxaline-5-carboxylic acid (44.0 mg, 253 muiotaetaomicronIota) and the reaction was stirred for 16 h at room temperature. For work-up, brine (45 ml) was added and the resulting precipitate was filtrated. The residue was dissolved in DMSO and the crude product was purified by HPLC (Method 6) to give after trituration with water the title product (54 mg)LC-MS (Method 4): Rt = 1 .15 min; MS (ESIpos): m/z = 453 [M+H]+1H-NMR (400 MHz, DMSO-d6) delta [ppm]: 1 .548 (5.49), 1 .581 (5.92), 1 .788 (2.48), 1 .820 (5.92), 1 .848 (5.61 ), 1 .901 (6.65), 1 .992 (4.72), 2.001 (4.87), 2.026 (6.99), 2.052 (3.52), 2.124 (6.90), 2.142 (12.41 ), 2.158 (6.99), 2.327 (1 .99), 2.539 (3.37), 2.668 (1 .96), 3.628 (7.72), 3.645 (13.55), 3.662 (7.1 1 ), 4.224 (3.62), 7.293 (2.54), 7.299 (2.85), 7.314 (5.06), 7.321 (5.27), 7.335 (3.13), 7.343 (3.03), 7.485 (5.24), 7.499 (5.85), 7.507 (5.06), 7.521 (4.14), 7.579 (5.33), 7.586 (5.36), 7.600 (5.39), 7.607 (5.00), 7.975 (4.54), 7.995 (7.88), 8.014 (5.33), 8.270 (7.1 1 ), 8.274 (7.05), 8.291 (6.50), 8.295 (6.50), 8.300 (3.92), 8.522 (7.02), 8.526 (6.80), 8.541 (6.59), 9.079 (16.00), 9.087 (15.66), 10.452 (3.80), 10.471 (3.65)

The synthetic route of 6924-66-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6924-66-9,Quinoxaline-5-carboxylic acid,as a common compound, the synthetic route is as follows.

6924-66-9, PyBOP (164 mg, 315 muiotaetaomicronIota) was added to a mixture of 8-amino-2-(2-chloro-4,6-difluorophenyl)- 2-azaspiro[4.5]decan-1 -one (isomer 1 , intermediate I56) (150 mg, 55 % purity, 262 muiotaetaomicronIota), quinoxaline-5-carboxylic acid (57.1 mg, 328 muiotaetaomicronIota) and N,N-diisopropylethylamine (230 muIota, 1 .3 mmol) in DMF (2.9 ml) and the mixture was stirred over night at room temperature. For workup, the reaction mixture was concentrated and the residue was purified by preparative HPLC to give the title compound 61 .3 mg (49 % yield). LC-MS (Method 1): Rt= 1.17 min; MS (ESIpos): m/z = 471 [M+H]+1H-NMR (400 MHz, DMSO-d6) delta [ppm]: 1.485 (0.75), 1.498 (0.85), 1.515 (2.19), 1.527 (2.38), 1.546 (2.66), 1.557 (2.60), 1.576 (1.35), 1.588 (1.22), 1.700 (5.70), 1.709 (5.70), 2.028 (2.94), 2.036 (3.07), 2.060 (2.85), 2.067 (2.63), 2.187 (3.41), 2.204 (6.95), 2.221 (4.07), 2.327 (1.88), 2.523 (4.79), 2.665 (1.41), 2.669 (1.91), 2.673 (1.41), 3.511 (1.03), 3.530 (2.32), 3.535 (2.00), 3.552 (2.88), 3.570 (1.41), 3.621 (1.47), 3.637 (2.60), 3.655 (1.91), 3.661 (2.16), 3.679 (0.97), 3.896 (1.16), 3.906 (1.44), 3.916 (1.19), 3.925 (1.41), 3.935 (1.13), 7.507 (1.47), 7.514 (2.07), 7.530 (2.22), 7.538 (4.04), 7.545 (3.19), 7.549 (3.01), 7.556 (2.54), 7.561 (3.13), 7.567 (3.23), 7.578 (1.78), 7.961 (3.57), 7.981 (5.01), 8.000 (4.26), 8.255 (4.76), 8.258 (4.85), 8.275 (4.23), 8.279 (4.07), 8.428 (4.60), 8.431 (4.54), 8.446 (4.32), 8.449 (3.98), 9.078 (16.00), 9.079 (15.72), 9.763 (3.66), 9.782 (3.60)

6924-66-9 Quinoxaline-5-carboxylic acid 776833, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

6924-66-9, Quinoxaline-5-carboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

6924-66-9, PyBOP (153 mg, 295 muiotaetaomicronIota) was added to a mixture of 8-amino-2-phenyl-2- azaspiro[4.5]decan-1 -one (isomer 1 ; Intermediate I22) (60.0 mg, 246 muiotaetaomicronIota), quinoxaline-5- carboxylic acid (56.3 mg, 307 muiotaetaomicronIota) and N,N-diisopropylethylamine (210 muIota, 1 .2 mmol) in DMF (1 .0 ml) and the mixture was stirred over night at room temperature. For work-up, water was added and the mixture was extracted with dichloromethane. The combined organic phases were washed with water, filtered through a silicone filter and concentrated to give the title compound 75.0 mg (75 % yield).LC-MS (Method 1 ): Rt= 1 .1 1 min; MS (ESIneg): m/z = 399 [M-H]- 1H-NMR (400 MHz, DMSO-d6) delta [ppm]: 1 .467 (0.86), 1 .477 (1 .02), 1 .498 (2.79), 1 .508 (2.90), 1 .528 (3.17), 1 .538 (3.28), 1 .559 (1.77), 1 .569 (1 .61 ), 1.643 (1.88), 1 .679 (8.70), 1.713 (3.60), 1 .721 (3.97), 1 .746 (1 .02), 1 .754 (0.97), 2.016 (3.44), 2.025 (3.65), 2.048 (3.33), 2.057 (3.06), 2.080 (5.58), 2.097 (9.99), 2.1 15 (5.74), 2.327 (0.75), 2.523 (1.61 ), 2.669 (0.75), 2.727 (0.91 ), 2.888 (1 .13), 3.792 (6.01 ), 3.809 (10.26), 3.827 (5.74), 3.869 (0.75), 3.887 (1 .40), 3.898 (1 .72), 3.906 (1 .34), 3.916 (1 .72), 3.925 (1.29), 7.1 18 (2.63), 7.136 (5.80), 7.155 (3.44), 7.361 (6.71 ), 7.382 (9.40), 7.401 (6.23), 7.690 (10.20), 7.709 (8.97), 7.959 (4.40), 7.978 (5.80), 7.980 (6.01 ), 7.999 (5.37), 8.253 (5.64), 8.256 (5.96), 8.273 (4.99), 8.277 (4.94), 8.429 (5.64), 8.433 (5.48), 8.448 (5.32), 8.451 (4.78), 9.070 (6.23), 9.075 (15.95), 9.079 (16.00), 9.083 (5.96), 9.767 (4.19), 9.785 (4.13)

6924-66-9 Quinoxaline-5-carboxylic acid 776833, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

6924-66-9, Quinoxaline-5-carboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

6924-66-9, PyBOP (156 mg, 300 muiotaetaomicronIota) was added to a mixture of quinoxaline-5-carboxylic acid (50.0 mg, 95 % purity, 273 muiotaetaomicronIota), 9-amino-2-(2-chloro-4-fluorophenyl)-2-azaspiro[5.5]undecan-1 -one (isomer 1 , Intermediate I62) (1 17 mg, 80 % purity, 300 muiotaetaomicronIota) and N,N-diisopropylethylamine (190 muIota, 1 .1 mmol) in DMF (2.8 ml) and the mixture was stirred for 5 h at room temperature. For work-up, the reaction mixture was concentrated and the residue was purified by flash chromatography (dichloromethane/methanol gradient, 0% -> 10% methanol) to give after trituration with methanol the title compound (45 mg).LC-MS (Method 1 ): Rt = 1 .19 min; MS (ESIpos): m/z = 467 [M+H]+1H-NMR (400 MHz, CHLOROFORM-d) delta [ppm] : 0.000 (6.00), 1.500 (16.00), 1.522 (1 16)1.532 (1.31), 1.540 (1.24), 1.550 (1.78), 1 560 (1 39), 1 568 (1 31) 1.578 (1 28), 1 592 (0 63)1.600 (0.57), 1.609 (0.49), 1.683 (1.07), 1 690 (1 09), 1 718 (1 20) 1.724 (1 26), 1 802 (1 09)1.809 (1.01), 1.837 (1.28), 1.843 (1.21), 1 892 (0 52), 1 904 (0 71) 1.920 (1 15), 1 927 (1 38)1.939 (1.65), 1.950 (2.10), 1.973 (3.19), 1 980 (1 79), 1 997 (1 21) 2.010 (1 63), 2 018 (2 38)2.044 (1.85), 2.055 (1.64), 2.068 (1.62), 2 078 (1 23), 2 089 (2 00) 2.099 (2 12), 2 117 (1 87)2.149 (1.86), 2.159 (1.59), 2.166 (1.37), 2 176 (1 05), 2 182 (1 06) 2.199 (1 86), 2 209 (1 45)2.233 (0.84), 2.242 (0.64), 3.417 (0.91), 3 431 (1 72), 3 447 (2 02) 3.462 (2 13), 3 475 (2 12)3.491 (1.41), 3.505 (0.65), 4.068 (0.47), 4 077 (0 49), 4 085 (0 89) 4.096 (1 13), 4 105 (0 89)4.114 (1.12), 4.124 (0.86), 4.142 (0.45), 6 931 (1 58), 6 938 (1 71) 6.951 (1 97), 6 953 (2 21)6.958 (2.18), 6.960 (2.43), 6.973 (1.84), 6 980 (1 97), 7 129 (3 74) 7.134 (3 68), 7 141 (4 30)7.143 (4.53), 7.151 (3.42), 7.154 (3.87), 7 161 (3 63), 7 165 (3 30) 7.180 (0 47), 7 840 (3 12)7.859 (3.92), 7.860 (4.21), 7.879 (3.46), 8 186 (3 53), 8 190 (3 76) 8.207 (3 23), 8 211 (3 17)8.813 (6.84), 8.817 (7.40), 8.840 (3.59), 8 844 (3 65), 8 859 (3 43) 8.863 (3 30), 8 902 (7 05)8.907 (6.43), 10.321 (1.64), 10.340 (1.64)

As the paragraph descriping shows that 6924-66-9 is playing an increasingly important role.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6924-66-9,Quinoxaline-5-carboxylic acid,as a common compound, the synthetic route is as follows.

To a solution of 8-amino-2-(2-chlorophenyl)-2-azaspiro[4.5]decan-1-one (isomer 1 Intermediate I35), (80.0 mg, 287 muetaiotaomicronIota) in DMF (2.6 ml) was added PyBOP (149 mg, 287 muiotaetaomicronIota), N,N-diisopropylethylamine (180 muIota, 1.0 mmol) quinoxaline-5-carboxylic acid (45.4 mg, 261 muiotaetaomicronIota) and the reaction was stirred for 6 h at room temperature. For work-up, water (45 ml) and methanol (2 ml) were added and the mixture was stirred for 1 h. The resulting precipitate was collected by filtration, washed with water/methanol (4:1) and dried to give the title compound 88.0 mg.LC-MS (Method 1 ): Rt = 1.11 min; MS (ESIpos): m/z = 435 [M+H]+ 1H-NMR (400 MHz, DMSO-d6) delta [ppm]: 1.511 (1.32), 1.535 (1.90), 1.553 (1.86), 1.566 (1.15), 1.583 (0.94), 1.701 (6.81), 1.710 (7.70), 1.718 (4.21), 1.727 (4.89), 2.031 (2.37), 2.040 (2.45), 2.062 (2.30), 2.072 (2.09), 2.151 (3.91), 2.167 (7.46), 2.185 (4.20), 2.327 (0.71), 2.523 (2.11), 2.669 (0.74), 3.639 (4.24), 3.657 (7.45), 3.674 (4.09), 3.893 (0.95), 3.902 (1.18), 3.912 (0.99), 3.921 (1.16), 3.931 (0.92), 7.366 (0.91), 7.378 (2.34), 7.384 (0.94), 7.389 (2.78), 7.395 (1.80) 7.397 (1.97), 7.408 (5.72), 7.414 (9.89), 7.417 (11.90), 7.426 (4.60), 7.431 (1.87), 7.563 (2.52) 7.567 (4.20), 7.570 (2.67), 7.582 (2.11), 7.585 (3.42), 7.588 (2.18), 7.962 (3.09), 7.980 (3.80) 7.983 (4.01), 8.001 (3.67), 8.255 (4.10), 8.259 (4.31), 8.276 (3.62), 8.279 (3.59), 8.432 (3.87) 8.436 (3.99), 8.451 (3.77), 8.454 (3.48), 9.074 (3.30), 9.079 (16.00), 9.086 (3.50), 9.774 (2.94) 9.793 (2.89), 6924-66-9

As the paragraph descriping shows that 6924-66-9 is playing an increasingly important role.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6924-66-9,Quinoxaline-5-carboxylic acid,as a common compound, the synthetic route is as follows.

6924-66-9, Example 25To a 50 mL flask containing 20 mL of DMF was added 1 mL of oxalyi chloride slowly and stirred for 10 min at RT. 100 mg of quinoxaline-5-carboxyltc acid was dissolved in 2 mL of the above solution and stirred for 5 min at RT. Then 50 mg of E was dissolved in 1 mL pyridine and added to the above solution. The reaction was completed in 5 min at RT and quenched with 1 mL NH4OH. The solvent was then evaporated under vacuum and the residue dissolved in CH3CN and water and purified with prep HPLC (0% to 95% water/ Acetonitriie) to afford 25 (26.7 mg, 54%). 1H-NMR (DMSO, 300 MHz): delta 9.04-9.02 (m, 2H), 8.49 (d, J = 3.9 Hz, 1 H), 8.31 (d, J = 6.0 Hz, 1 H), 8.24 (d, J = 8.4 Hz, 1 H), 7.94 (t, J – 7.2 Hz, 1 H), 7.73 (d, J = 6.9 Hz, 1 H), 7.62-7.57 (m, 2H), 7.22 (t, J = 8.4 Hz, 1 H), 7.06 (t, J = 6.6 Hz, 1 H)1 6.98 (d, J = 7.8 Hz, 2H), 6.80 (d, J = 7.5 Hz, 1 H), 4.83 (me, 1 H), 3.18-3.06 (m, 3H), 2.77-2.75 (m, 1 H), 0.65 (m, 2H), 0.51 (m, 2H).LCMS m/z [M+Hj+ C32H25N5O3S requires: 560.64. Found 560.08 HPLC Tr (min), purity %: 3.36, 98%

6924-66-9 Quinoxaline-5-carboxylic acid 776833, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; GILEAD SCIENCES, INC.; MACKMAN, Richard, L.; SPERANDIO, David; YANG, Hai; WO2011/5842; (2011); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

6924-66-9,6924-66-9, Quinoxaline-5-carboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Step 1: N-Q-chlorophenvDquinoxalme-S-carboxamideA solution (0.1 M) of quinoxaline-5-carboxylic acid in CH2Ck was treated with DIPEA (2.2 eq.), 3- chloroaniline (1.1 eq.) and HATU (1.1 eq.). The reaction mixture was stirred at RT overnight. The solution was diluted with EtOAc and the organic phase was washed with aqueous NaHC?3 (saturated solution) and dried. Evaporation of the solvent gave a crude that was washed with MeCN and filtered off affording (93%) the title compound as a solid; MS (ES+) m/z 284, 286 (M+H)+.

The synthetic route of 6924-66-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA; WO2007/28789; (2007); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

6924-66-9,6924-66-9, Quinoxaline-5-carboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

PyBOP (100 mg, 193 muiotaetaomicronIota) was added to a mixture of 8-amino-2-(3,5-difluorophenyl)-2- azaspiro[4.5]decan-1-one (isomer 1; Intermediate I28) (50.0 mg, 161 muiotaetaomicronIota), quinoxaline-5- carboxylic acid (30.8 mg, 177 muiotaetaomicronIota) and N,N-diisopropylethylamine (140 muIota, 800 muiotaetaomicronIota) in DMF (1.8 ml) and the mixture was stirred over night at room temperature. For work-up, the reaction mixture was concentrated and the residue was stirred with methanol. The precipitate was collected by filtration, washed with water and methanol and then dried to give the title compound 53.5 mg (76 % yield).LC-MS (Method 1): Rt= 1.23 min; MS (ESIpos): m/z = 437 [M+H]+1H-NMR (400 MHz, DMSO-d6): delta [ppm] = 9.78 (d, 1H), 9.10-9.05 (m, 2H), 8.44 (dd, 1H), 8.27 (dd, 1H), 7.98 (dd, 1H), 7.56-7.48 (m, 2H), 7.02 (tt, 1H), 3.96-3.78 (m, 3H), 2.14-2.00 (m, 4H), 1.75-1.62 (m, 4H),

6924-66-9 Quinoxaline-5-carboxylic acid 776833, aquinoxaline compound, is more and more widely used in various fields.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

6924-66-9, Quinoxaline-5-carboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

PyBOP (149 mg, 287 muiotaetaomicronIota) was added to a mixture of quinoxaline-5-carboxylic acid (45.4 mg, 261 muiotaetaomicronIota), 8-amino-2-(3-chlorophenyl)-2-azaspiro[4.5]decan-1 -one (isomer 1 , Intermediate I50) (80.0 mg, 287 muiotaetaomicronIota) and N,N-diisopropylethylamine (180 muIota, 1 .0 mmol) in DMF (2.6 ml) and the mixture was stirred over night at room temperature. For work-up, water (45 ml) and methanol (2 ml) were added and the mixture was stirred for 4 h. The precipitate was collected by filtration, washed with a mixture of water and methanol (4:1 ) and dried to give the title compound 109 mg (93 % yield).LC-MS (Method 1 ): Rt= 1 .22 min; MS (ESIpos): m/z = 435 [M+H]+ 1H-NMR (400 MHz, DMSO-d6) delta [ppm]: 1 .494 (2.45), 1 .506 (2.64), 1 .524 (2.94), 1 .535 (2.88) 1 .555 (1 .60), 1 .566 (1.50), 1 .650 (1 .19), 1.660 (1 .47), 1.683 (10.64), 1.706 (3.13), 1 .714 (3.63) 2.012 (3.13), 2.023 (3.32), 2.046 (3.09), 2.055 (2.76), 2.081 (5.42), 2.099 (9.45), 2.116 (5.61 )2.327 (0.87), 2.518 (2.62) 2.523 (1.85), 2.669 (0.91 ), 2.729 (0.63), 2.888 (0.76), 3.804 (5.72) 3.813 (1 .63), 3.822 (9.67) 3.829 (1.66), 3.839 (5.52), 3.888 (1.32), 3.898 (1 .62), 3.907 (1 .29) 3.917 (1 .57), 3.927 (1 .22) 7.189 (3.31 ), 7.191 (3.67), 7.194 (3.70), 7.196 (3.56), 7.209 (3.89) 7.21 1 (4.22), 7.214 (4.32) 7.216 (4.10), 7.394 (5.26), 7.415 (9.49), 7.435 (5.33), 7.589 (3.61 ) 7.591 (3.98), 7.594 (3.89) 7.596 (3.88), 7.610 (3.00), 7.61 1 (3.01 ), 7.615 (3.35), 7.617 (2.95) 7.910 (5.41 ), 7.916 (10.28), 7.921 (5.48), 7.960 (5.22), 7.977 (5.64), 7.981 (6.35), 7.999 (5.99) 8.253 (6.1 1 ), 8.257 (6.58), 8.274 (5.36), 8.278 (5.38), 8.430 (6.23), 8.433 (6.27), 8.448 (5.77) 8.452 (5.22), 9.069 (7.93), 9.074 (16.00), 9.080 (15.91 ), 9.084 (7.60), 9.770 (4.17), 9.788 (4.13), 6924-66-9

The synthetic route of 6924-66-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; BUCHGRABER, Philipp; EIS, Knut; WAGNER, Sarah; SUeLZLE, Detlev; VON NUSSBAUM, Franz; BENDER, Eckhard; LI, Volkhart, Min-Jian; LIU, Ningshu; SIEGEL, Franziska; LIENAU, Philipp; (248 pag.)WO2018/78005; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider