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Facile synthesis of quinoxalinyl-2-oxyphenols are described.The condensation of 2-chloroquinoxalines with three molar equivalent of dihydroxybenzene in basic medium gave preferentially quinoxalinyl-2-oxyphenols, which involves nucleophilic cleavage of the initially formed bis(quinoxalinyl-2-oxy)benzenes by an excess of dihydroxybenzene.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1977 | ChemSpider

 

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Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of using these chemical entities, e.g., for treatment of cancer are described

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Quinoxaline – Wikipedia,
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The present invention provides for a method for treating a disease condition associated with PI3-kinase alpha and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase alpha and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth.

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Quinoxaline – Wikipedia,
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This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1972 | ChemSpider

 

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Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1974 | ChemSpider

 

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Chemical entities that are quinoxaline kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

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Quinoxaline – Wikipedia,
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Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.

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Quinoxaline – Wikipedia,
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The present invention relates novel 6-6 bicyclic aromatic ring substituted nucleoside analogues of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

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Quinoxaline – Wikipedia,
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Pharmaceutical compounds, their methods of manufacture, and methods of treatment of mammals with pharmaceutical compounds are provided.

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Quinoxaline – Wikipedia,
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Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.

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Reference:
Quinoxaline – Wikipedia,
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