Category: quinoxaline

Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C9H7BrN2O, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 82019-32-7

A novel and efficient approach to the C(sp2)?H/C(sp3)?H oxidative coupling of quinoxalin-2(1H)-ones with methylarenes by using CuI as catalyst is reported. Various substrates were well tolerated in this methodology and the desired products were given in moderate-to-good yields. This reaction features good functional group compatibility and broad substrate scope.

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Quinoxaline | C8H6N1923 | ChemSpider

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 2,3-Dichloroquinoxaline, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 2213-63-0

2,3-Dichloroquinoxaline has been cyclo-condensed with 2-aminopyridine, 2-aminothiazoles, 2-aminothiadiazoles, 2-aminobenzimidazole and 2-mercaptobenzimidazole to give the corresponding novel heterocyclic systems.The reaction of 2,3-dichloroquinoxaline with thioacetamide has also been studied.

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Quinoxaline | C8H6N1321 | ChemSpider

1448-87-9, Name is 2-Chloroquinoxaline, belongs to quinoxaline compound, is a common compound. COA of Formula: C8H5ClN2In an article, once mentioned the new application about 1448-87-9.

The oxidation reaction of a series of quinoxaline derivatives, using KMnO4 in the presence or absence of NaOH, are described.Neutral oxidation of 2-chloro- and 2,3-dichlorodioxalines 2-4 afforded the corresponding chloro- and dichloropyrazinedicarboxilic acids 13 and 14 in good yield.On the other hand, oxidation of quinoxalin-2(1H)-one and 1,4-dihydroquinoxaline-2,3-dione derivatives in alkaline medium gave different products, with the quinoxalin-2(1H)-one (5) forming 1,4-dihydroquinoxaline-2,3-dione (9), while various substituted quinoxalin-2,3-dione derivatives (see 9-11) gave a new type of dimeric products.The structural assignments for the new compounds were based on spectroscopic data.

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Quinoxaline | C8H6N649 | ChemSpider

Related Products of 2379-56-8, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2379-56-8, Name is 6-Nitroquinoxaline-2,3-dione, molecular formula is C8H3N3O4. In a Article，once mentioned of 2379-56-8

We have developed a novel fluorescent scaffold 4 which is a 9-nitro-2,3-dihydro-1H-pyrimido[1,2-a]quinoxalin-5-amine derivative from the reaction between di-tert-butyl but-2-ynedioate and a quinoxaline molecule containing a dimethyl amine side tail in high yield. The synthesis of scaffold 4 involves an sp3 C-N bond cleavage mechanism which is not very common. The scaffolds 4 is emissive in the visible range lambdaem ? (517-540) nm with large stokes shifts (5005-6378) cm-1 in ethanol. Laser confocal microscopy of the live HepG2 cells treated with compound 4f shows that it can be used for live cell imaging in nanomolar concentrations.

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Related Products of 17056-99-4, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 17056-99-4, Name is Quinoxalin-5-ol, molecular formula is C8H6N2O. In a Patent，once mentioned of 17056-99-4

The invention aims to allow a curable composition to have an extended working phase followed by a short time period in which said compound becomes fully cured. This is achieved by the provision of a curable composition comprising the following components: a) at least one polyether and/or at least one polyacrylic acid ester with at least one reactive silyl group as an end-group; b) at least one organotin compound; and c) at least one compound that does not contain any tin or silicon atoms and that has at least two functional groups. Said groups are selected from the following: carboxy, carbonyl or hydroxy groups, or nitrogen atoms that are part of a ring system with aromatic character. In addition, the invention relates to a method for producing such a composition, and to the use thereof as an adhesive, a sealant or as a coating material.

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Quinoxaline | C8H6N105 | ChemSpider

Reference of 130345-50-5, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 130345-50-5, Name is Quinoxaline-6-carbaldehyde, molecular formula is C9H6N2O. In a Article，once mentioned of 130345-50-5

Aim: Quinoxaline-1,4-dioxide derivatives are synthetic heterocyclic compounds with multiple biological and pharmacological effects. In this study, we investigated the bioactivity of five quinoxaline-1,4-di-N-oxides derivatives in different animal cell lines. Materials & methods: Using in vitro cell cultures, we evaluated the influence of quinoxaline-1,4-dioxide, 2-methylquinoxaline-1,4-dioxide, 2-amino-3-cyanoquinoxaline-1,4-dioxide, 3-methyl-2-quinoxalinecarboxamide-1,4-dioxide and 2-hydroxyphenazine-N,N-dioxide (2HF) in the viability, migration and proliferation of nonmalignant (3T3-L1 and human dermal microvascular endothelial cell) and malignant (B16-F10, MeWo, GL-261 and BC3H1) cell lines. Results: The viability IC50 concentrations for each quinoxaline-1,4-di-N-oxide derivative were calculated, and a concomitant reduction of migration and proliferation was observed mainly in malignant cell lines. Conclusion: 2HF exhibited potent anti-viability, anti-migration and anti-proliferative actions selectively in tumor cells, nevertheless more studies are required to further investigate 2HF promising biologic effects.

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18514-76-6, Name is 5-Nitroquinoxaline, belongs to quinoxaline compound, is a common compound. Recommanded Product: 5-NitroquinoxalineIn an article, once mentioned the new application about 18514-76-6.

A rhodium(iii)-catalyzed indole-directed aryl C-H bond carbenoid insertion cascade of 2-arylindoles with diazo compounds has been developed. This method provides a rapid access to 1,2-benzocarbazoles and isoquinoline-based polycyclic heteroaromatics with a broad range of functional group tolerance. The primary evaluation of the photoluminescence property of the novel extended pi-systems indicated that these heteroarenes could be potentially used in the field of optoelectronic materials.

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Quinoxaline | C8H6N932 | ChemSpider

Reference of 1448-87-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 1448-87-9, Name is 2-Chloroquinoxaline,introducing its new discovery.

Modifications to the ETA/B mixed type compounds 1 (Ro. 46-2005) and 2 (bosentan) were performed. Introduction of a pyrimidine group into 1 resulted in a dramatic increase in affinity for the ETA receptor, and the subsequent optimization of substituents on the pyrimidine ring led us to the discovery of N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)- 4pyrimidinyl)-4-tert-butylbenzenesulfonamide (7k), which showed an extremely high affinity for the human cloned ETA receptor (Ki=0.0042±0.0038 nM) and an ETA/B receptor selectivity up to 29 000 (Ki=130±50 nM for the human cloned ETB receptor). The compound was designed on the hypothesis that the hydrogen atom of the hydroxyl group in 1 and 2 played a role not as a proton donor but as an acceptor in the possible hydrogen bonding with Tyr129. Since the incorporation of a pyrimidinyl group into the hydroxyethoxy side chain of the nonselective antagonist (1) dramatically enhanced both the ETA receptor affinity and selectivity, and since similar results were obtained from the benzene analogues, we put forward the hypothesis that a “pyrimidine binding pocket” might exist in the ETA receptor.

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Quinoxaline | C8H6N638 | ChemSpider

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 2-Chloroquinoxaline, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 1448-87-9

An efficient approach to synthesis of various substituted 3-azabicyclo[3.2.0]heptane-derived building blocks based on [3+2] cycloaddition of cyclobut-1-eneraboxylic acid ester and in situ generated azomethine ylide was developed and applied on multigram scale. The utility of 1,3-disubstituted 3-azabicyclo[3.2.0]heptane scaffold was demonstrated by additional structural analysis using exit vector plot (EVP) tool, and tested in parallel synthesis of compound library.

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Quinoxaline | C8H6N597 | ChemSpider

Electric Literature of 2213-63-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a Article，once mentioned of 2213-63-0

An unprecedented AlCl3-mediated method has been developed involving aromatic C-H bond addition to an alkyne and heteroarylation of an arene in a single pot leading to densely functionalized novel olefins, e.g. 2-(2,2-diarylvinyl)-3-arylquinoxalines, as potential inhibitors of sirtuins.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1476 | ChemSpider