Category: quinoxaline

On February 25, 2014, Lu, Chiyu; Shi, Jiahao; Li, Shaoqin published an article.Electric Literature of 34413-35-9 The title of the article was Fumigation activities of 13 kinds of essential oils and anethole against the adult of Tribolium castaneum (Herbst). And the article contained the following:

On the condition of dosage of 20 μL/L, the fumigation effects of 13 kinds of essential oils against the adult of Tribolium castaneum (Herbst) were studied. The results showed that the effect of Illicium verum oil was better than that of the other essential oils. The mortality rate reached 100% under the 24 h exposure. The results of fumigation toxicity of Illicium verum oil against adults showed as follows: with the extension of exposure time, the fumigation effect enhanced significantly. When fumigation time increased from 12 h to 72 h, the LC50 decreased from 13.88 μL/L to 5.08 μL/L. Then 21 kinds of ingredients from Illicium verum oil were found by GC-MS; the main component was anethole, and the relative content was 79.81%. The fumigation toxicity results of anethole against adults showed an increase of the fumigation time from 12 h to 72 h; and the LC50 decreased from 7.76 μL/L to 3.36 μl/L. The LC50 of anethole was lower than that of Illicium verum oil. The fumigation effect of anethole against Tribolium castaneum adult was stronger than that of Illicium verum oil. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Electric Literature of 34413-35-9

The Article related to tribolium essential oil anethole adult fumigation activity illicium, Agrochemical Bioregulators: Invertebrate and other aspects.Electric Literature of 34413-35-9

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On September 21, 2020, Zarini, Daniele; Sangion, Alessandro; Ferri, Emanuele; Caruso, Enrico; Zucchi, Sara; Orro, Alessandro; Papa, Ester published an article.Related Products of 34413-35-9 The title of the article was Are In Silico Approaches Applicable As a First Step for the Prediction of e-Liquid Toxicity in e-Cigarettes?. And the article contained the following:

Recent studies have raised concerns about e-cigarette liquid inhalation toxicity by reporting the presence of chems. with European Union CLP toxicity classification. In this scenario, the regulatory context is still developing and is not yet up to date with vaping current reality. Due to the paucity of toxicol. studies, robust data regarding which components in tent. In this study we applied computational methods for studied chems. as a useful tool for predicting the acute toxicity of chems. contained in e-liquids The purpose of t the potential health concerns associated with e-liquid ingredients, (b) to prioritize e-liquid ingredients by calculating the e-tox index, and (c) to estimate acute toxicity of e-liquid mixtures QSAR models were generated using QSARINS software to fill the acute toxicity data gap of 264 e-liquid ingredients. As a second step, the potential acute toxicity of e-liquids mixtures was evaluated. Our preliminary data suggest that a computational approa serve as a roadmap to enable regulatory bodies to better regulate e-liquid composition and to contribute to consumer health protection. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Related Products of 34413-35-9

The Article related to toxicity electronic cigarette liquid qsar model, Toxicology: Methods (Including Analysis) and other aspects.Related Products of 34413-35-9

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Zhang, Qiang; Yu, Xue-lian; Chen, Liang; Xin, Xiu-lan; Chang, Li; Wen, Yi; Zhang, Hai-ting published an article in 2017, the title of the article was Analysis on aromatic compositions of red raspberry vinegar fermented with nature and pure breed.SDS of cas: 34413-35-9 And the article contains the following content:

The aromatic compositions of red raspberry vinegar fermented with one step and two steps under two different fermentation processes were analyzed by headspace solid-phase micro-extraction (HS-SPME) coupled to gas chromatog.-mass spectrometry (GC-MS). The results showed that a total of 84 kinds of aroma components were identified under the two different vinegar-making processes. 32 Kinds of aroma components were detected in vinegars fermented nature and pure breed. The main aroma components in two red raspberry vinegars were benzene ethanol, benzoic acid Et ester, Et acetate, α-ionone and β-ionone of which, the relative contents of nature fermented vinegar were 26.12%, 9.91%, 8.51%, 5.64% and 4.09% resp., and the relative contents of pure breed fermented vinegar were 22.39%, 3.43% 32.68%, 3.32% and 2.81% resp. According to the sensory evaluation, the vinegar fermented with pure breed fermentation was superior to that the vinegar fermented with nature fermentation Nature fermented red raspberry vinegar was clear and transparent, the color was full, the taste was mellow and soft, the fragrance was lovely and lasting, and of more red raspberry vinegar typical flavor. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).SDS of cas: 34413-35-9

The Article related to aromatic composition red raspberry vinegar fermentation breed, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.SDS of cas: 34413-35-9

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On December 20, 2012, Cao, Sheldon; Popovici-Muller, Janeta; Salituro, Francesco G.; Saunders, Jeffrey; Tan, Xuefei; Travins, Jeremy; Yan, Shunqi; Ye, Zhixiong published a patent.Reference of 5-Chloroquinoxaline The title of the patent was Pyridinyl-heterocycles as isocitrate dehydrogenase 1 inhibitors and their preparation, therapeutically active compositions and their methods of use. And the patent contained the following:

Provided are compounds of formula I. pharmaceutically acceptable salts thereof, use of those compounds for treating cancer and pharmaceutical compositions comprising those compounds Compounds of formula I wherein Y is NR5, NR5CH2, CH2NR5 and CHR5; m is 0, 1, 2 and 3; R1a and R1b are independently H, C1-4 alkyl, heterocyclyl, etc.; R2 is (un)substituted Ph, (un)substituted 3- to 7-membered cycloalkyl, C2-4 alkyl and CF3; each R3 is independently halo,C1-4 fluoroalkyl, Ph, heteroaryl, etc.; R4 is H, CN, halo, C1-4 alkoxy, etc.; R5 is alkanoyl, alkenoyl, sulfonyl, etc.; and pharmaceutically acceptable salts thereof, are claimed. Example compound II was prepared by a multistep procedure (procedure given). All the invention compounds were evaluated for their IDH1 R132H inhibitory activity. From the assay, it was determined that compound II exhibited IC50 value in the range of > 1 μM and ≤ 5 μM. The experimental process involved the reaction of 5-Chloroquinoxaline(cas: 62163-09-1).Reference of 5-Chloroquinoxaline

The Article related to pyridinyl heterocycle preparation idh1 inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Diazepines and other aspects.Reference of 5-Chloroquinoxaline

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On July 31, 2011, Zhang, Ying; Yu, Shijun; Zhang, Pengfei; Zhang, Longwa; Fan, Meizhen published an article.Recommanded Product: 5,6,7,8-Tetrahydroquinoxaline The title of the article was Analysis of volatile components of Flammulina velutipes and Agrocybe chaxingu. And the article contained the following:

The volatile components in fruiting bodies of Flammulina velutipes and Agrocybe chaxingu were extracted with simultaneous distillation and extraction (SDE) and analyzed by gas chromatog.-mass spectrometer (GC-MS). There were 32 and 31 volatile components identified in Flammulina velutipes and Agrocybe chaxingu, resp. Phenols and aldehydes were the dominant volatiles. The main component of Flammulina velutipes were identified as 2,6-di-tert-butyl-4-Me phenol, benzeneacetaldehyde, 5-methylfuranal, 2-methyl-phenol, 2,5-diethyl-pyrazine and indole. Among 31 components in Agrocybe chaxingu, 2,6-di-tert-butyl-4-Me phenol, 2-pentyl-furan, benzeneacetaldehyde, phenylethyl alc., 2-methyl-heptane and indole were the components. The study provided exptl. foundation for comprehensive utilization of mushroom. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Recommanded Product: 5,6,7,8-Tetrahydroquinoxaline

The Article related to flammulina agrocybe volatile component gc ms, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Recommanded Product: 5,6,7,8-Tetrahydroquinoxaline

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Ji, Xiao-dong; Zhao, Ya-li; Wu, Guo-chen; Cai, Xian-kun published an article in 2010, the title of the article was Analysis of volatile aroma components of fried peanuts.Recommanded Product: 34413-35-9 And the article contains the following content:

Peanut is rich in nutrients and the flavor of its products varies according to the processing technol. Peanut was roasted, pressure steamed, extracted by simultaneous distillation and extraction (SED) and then condensed for GC-MS anal. of its volatile aroma components. Aldehydes, pyrazine, alc., ketone and hydroxybenzene were found in the volatile aroma of processed peanuts, with their contents for 53.29%, 14.66%, 6.13%, 1.03%, and 7.73%, resp. And pyridine, pyrrole, thiophene, and others accounted for 17.02%. Besides, two important fragrances, 2-acetyl-l-pyrroline and 2-methoxy-4-vinylphenol, were also detected in the volatile aroma of processed peanuts. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Recommanded Product: 34413-35-9

The Article related to fried peanut volatile aroma component, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Recommanded Product: 34413-35-9

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On December 31, 1998, El-Kayati, S. M.; Fadel, H. H. M.; Abdel Mageed, M. A.; Farghal, S. A. published an article.Name: 5,6,7,8-Tetrahydroquinoxaline The title of the article was Heat and storage effects on the flavor of peanuts. And the article contained the following:

The peanut varieties, Giza 4 and Giza 5 were subjected to different heat treatments such as drying in solar drier at air speed 0.5 and 2 m/s with average temperature 45 and 60° and heating in oven at 120 and 150°. The sensory evaluation of the 2 varieties showed insignificant differences among varieties and heating processes. A correlation between the sensory and instrumental data was found. The high sensory scores of samples heated at 150° were attributed to the presence of high concentration of pyrazines which were thought to contribute to flavor and aroma of fresh roasted peanut. A comparative study between the main chem. classes retained in peanut samples after storage for 3 mo at room temperature showed that the aldehydes derived lipids increased in the solar dried samples. The antioxidative components produced via Maillard reaction resulted in oxidative stability of the samples heated in oven. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Name: 5,6,7,8-Tetrahydroquinoxaline

The Article related to peanut flavor heat storage volatile, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Name: 5,6,7,8-Tetrahydroquinoxaline

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On October 18, 1988, Kato, Shozo; Ishizaki, Masahiko; Osada, Seiji published a patent.Recommanded Product: 62163-09-1 The title of the patent was Preparation of halogenated heterocydes as intermediates for agrochemicals and drugs. And the patent contained the following:

Polyhalogenated heterocycles are dehalogenated in H2O and/or alcs. in the presence of Fe powder and inorganic bases to give halogenated heterocycles. The experimental process involved the reaction of 5-Chloroquinoxaline(cas: 62163-09-1).Recommanded Product: 62163-09-1

The Article related to halogenated heterocycle intermediate drug agrochem, dehalogenation polyhaloheterocycle, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.Recommanded Product: 62163-09-1

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On May 2, 2003, Skupinska, Krystyna A.; McEachern, Ernest J.; Baird, Ian R.; Skerlj, Renato T.; Bridger, Gary J. published an article.Electric Literature of 34413-35-9 The title of the article was Enzymatic Resolution of Bicyclic 1-Heteroarylamines Using Candida antarctica Lipase B. And the article contained the following:

Candida antarctica lipase B has been used to kinetically resolve a structurally diverse series of bicyclic 1-heteroaryl primary amines, e.g. 8-amino-5,6,7,8-tetrahydroquinoline, 5-amino-5,6,7,8-tetrahydroquinoxaline, etc., by enantioselective acetylation. High yields of either enantiomer could be obtained with excellent enantioselectivity (90-99% ee), while the undesired enantiomer could, in some cases, be recycled by thermal racemization. The absolute stereochem. of the products was confirmed by an X-ray crystallog. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Electric Literature of 34413-35-9

The Article related to amine heteroaryl bicyclic acetylation enzymic resolution lipase, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.Electric Literature of 34413-35-9

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

On January 31, 1981, Poradowska, Henryka; Kaniewska, Alicja published an article.Formula: C8H5ClN2 The title of the article was The mass spectra of halo derivatives of quinoxaline. And the article contained the following:

The mass spectra of 17 haloquinoxalines I (R-R3 = H, Br, Cl, Me) were recorded. All I gave mol.-ion peaks with typical isotopic ratios. The fragmentation path depended on the position of the halo atom: pyrazine-bound halo derivatives fragmented primarily via elimination of a halogen radical with insignificant cyanogen halide elimination, whereas benzene-bound halo derivatives fragmented via successive elimination of 2 RCN mols. (R = H, Me). The experimental process involved the reaction of 5-Chloroquinoxaline(cas: 62163-09-1).Formula: C8H5ClN2

The Article related to haloquinoxaline mass spectra, quinoxaline halo mass spectra, methylquinoxaline halo mass spectra, Physical Organic Chemistry: Spectral and Related Studies and other aspects.Formula: C8H5ClN2

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider