Tag: 176.22

Hindered amines. Part 4. 3,3-Dialkyl-1,2,3,4-tetrahydro-2-quinoxalinones and cis- and trans-3,3-dialkyldecahydro-2-quinoxalinones was written by Lai, John T.. And the article was included in Synthesis in 1982.SDS of cas: 80636-30-2 This article mentions the following:

Tetrahydroquinoxalinones I [R = H; R¹ = Me, R² = Me, hexyl; R¹R² = (CH₂)₄, (CH₂)₅] were obtained by treating o-(H₂N)₂C₆H₄ with R¹R²CO and CHCl₃. I (R = 6-Me, 7-Me, 6-Cl, 7-Cl, R¹ = R² = Me) were obtained from 3,4-(H₂N)₂C₆H₃R and Cl₃CCMe₂OH. Rh-C hydrogenation of I (R = H) gave cis–II. trans–II were obtained from HOCR¹R²CN and 1,2-cyclohexanediamine. In the experiment, the researchers used many compounds, for example, 3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (cas: 80636-30-2SDS of cas: 80636-30-2).

3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (cas: 80636-30-2) belongs to quinoxaline derivatives. Quinoxaline derivatives are important constituents of pharmacologically active compounds, including antibacterial, antibiotic and antineoplastic, antifungal, anti-inflammatory and analgesic drugs. Quinoxaline and its analogues may also be formed by reduction of amino acids substituted 1,5-difluoro-2,4-dinitrobenzene (DFDNB),One study used 2-iodoxybenzoic acid (IBX) as a catalyst in the reaction of benzil with 1,2-diaminobenzene.SDS of cas: 80636-30-2

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

A Novel Palladium-Catalyzed Synthesis of 1,2-Dihydroquinoxalines and 3,4-Dihydroquinoxalinones was written by Soederberg, Bjoern C. G.;Wallace, Jeffery M.;Tamariz, Joaquin. And the article was included in Organic Letters in 2002.Reference of 80636-30-2 This article mentions the following:

Reactions of enamines, derived from 2-nitroanilines and α-substituted aldehydes, with carbon monoxide (6 atm) in the presence of a catalytic amount of bis(dibenzylideneacetone)palladium(0) (Pd(dba)₂) and 1,3-bis(diphenylphosphino)propane (dppp) afford readily separated mixtures of 1,2-dihydroquinoxalines and 3,4-dihydroquinoxalinones. Addition of a catalytic amount of 1,10-phenanthroline to the reaction mixture substantially improved the yield of products. In the experiment, the researchers used many compounds, for example, 3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (cas: 80636-30-2Reference of 80636-30-2).

3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (cas: 80636-30-2) belongs to quinoxaline derivatives. Condensed heterocycles of quinoxalines have become attractive targets in synthetic and medicinal chemistry due to their significant biological activities. Quinoxaline-1,4-di-N-oxide derivatives have shown to improve the biological results and are endowed with anti-viral, anti-cancer, anti-bacterial, and anti-protozoal activities with application in many other therapeutic areas.Reference of 80636-30-2

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Efficient synthesis of useful heterocycles via transition metal-catalyzed cascade processes was written by Tanimori, Shinji;Inaba, Ushio;Kato, Yoshihiro;Ura, Haruna;Kashiwagi, Hiroaki;Nishimura, Takeshi;Kirihata, Mitsunori. And the article was included in Research on Chemical Intermediates in 2014.Electric Literature of C10H12N2O This article mentions the following:

This paper reports our recent results from synthesis of some useful heterocycles, for example oxazolidinones, indoles, and quinoxalinones, by transition metal-catalyzed cascade processes. The scope and limitations of these procedures and the reaction mechanism for formation of the heterocycles are also discussed. In the experiment, the researchers used many compounds, for example, 3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (cas: 80636-30-2Electric Literature of C10H12N2O).

3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (cas: 80636-30-2) belongs to quinoxaline derivatives. Quinoxaline derivatives are important constituents of pharmacologically active compounds, including antibacterial, antibiotic and antineoplastic, antifungal, anti-inflammatory and analgesic drugs. Modifying quinoxaline structure it is possible to obtain a wide variety of biomedical applications, namely antimicrobial activities and chronic and metabolic diseases treatment.Electric Literature of C10H12N2O

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider