Tag: 1865-11-8

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1865-11-8,Methyl quinoxaline-2-carboxylate,as a common compound, the synthetic route is as follows.

Methanolic ammonia (10 ml, 7N) was added to a compound methyl quinoxaiine-2-carhoxylate (1.1 g, 5.85 rnmol) at 0 C and the reaction mixture was allowed to stir at room temperature for overnight. The reaction mixture was concentrated under reduced pressure and the crude material was purified by column chromatography on silica gel using Ethyl acetate/ilexane as an eluent to give the desired product quinoxaline-2-carboxamide (0.98 g, 566 mmoi, 97 % ) as a solid., 1865-11-8

1865-11-8 Methyl quinoxaline-2-carboxylate 478049, aquinoxaline compound, is more and more widely used in various.

Reference£º
Patent; PI INDUSTRIES LTD.; SAXENA, Rohit; PANMAND, Deepak Shankar; JENA, Lalit Kumar; SRIVASTAVA, Khushboo; RAJU, Jella Rama; MANJUNATHA, Sulur G; SAMANTA, Jatin; GARG, Ruchi; AUTKAR, Santosh Shridhar; VENKATESHA, Hagalavadi M; GADAKH, Ramdas Balu; KLAUSENER, Alexander G. M.; POSCHARNY, Konstantin; (219 pag.)WO2018/116072; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1865-11-8,Methyl quinoxaline-2-carboxylate,as a common compound, the synthetic route is as follows.

General procedure: All the solids and liquids were introduced on the platform whichis inertized under argon. [Ir(cod)Cl]2 (3.4 mg; 0.005 mmol), the ligands (0.011 mmol for the bisphosphines and 0.022 mmol for the monophosphines) were automatically weighted into vials and solubilized into the chosen solvents (5 mL). Iodine solution (0.025 mmol, 12.7 mg in 2 mL of solvent) was prepared in a separated vial. The catalytic solutions were introduced into the autoclaves and the mixtures were stirred for 30 min for preparing the precatalysts. The substrate (1 mmol) was then added in each autoclave. Then, iodine in solution (0.1 mmol) was introduced. The reactors were then purged with molecular hydrogen three times and pressurized at the desired pressure of dihydrogen. The stirring was started once the desired temperature was reached. At the end of the assays, the reactors were returned at ambient temperature and depressurized. The catalytic mixtures were filtered separately through pads of silica gel. Then, GC analysis and examination of 1HNMR spectra allowed determining the conversions. The enantiomeric excesses were determined by HPLC analysis., 1865-11-8

The synthetic route of 1865-11-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Maj, Anna M.; Heyte, Svetlana; Araque, Marcia; Dumeignil, Franck; Paul, Sebastien; Suisse, Isabelle; Agbossou-Niedercorn, Francine; Tetrahedron; vol. 72; 10; (2016); p. 1375 – 1380;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider