Tag: 225.0421

Zhang, Lixi et al. published their research in Molecular Catalysis in 2022 | CAS: 55687-34-8

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Condensed heterocycles of quinoxalines have become attractive targets in synthetic and medicinal chemistry due to their significant biological activities. Quinoxaline-1,4-di-N-oxide derivatives have shown to improve the biological results and are endowed with anti-viral, anti-cancer, anti-bacterial, and anti-protozoal activities with application in many other therapeutic areas.Category: quinoxaline

Visible-light-induced decarboxylative alkylation of quinoxalin-2(1H)-ones with phenyliodine(III) dicarboxylates by cerium photocatalysis was written by Zhang, Lixi;He, Jingwen;Zhang, Pengfei;Zheng, Kai;Shen, Chao. And the article was included in Molecular Catalysis in 2022.Category: quinoxaline This article mentions the following:

3-Alkylquinoxalin-2(1H)-ones I [R1 = H, 6-Me, 7-Cl, etc.; R2 = Me, Et, Pr, propargyl, allyl, Bn; R3 = Me, Et, cyclopropyl, etc.] were prepered via visible-light-induced decarboxylative alkylation of quinoxalin-2(1H)-ones with phenyliodine(III) dicarboxylate using inexpensive CeCl3 as photocatalyst. Novel protocol had advantages of mild conditions, high yields and good substrate scope. Control experiments indicated that radical mechanism was responsible for the present transformation. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Category: quinoxaline).

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Condensed heterocycles of quinoxalines have become attractive targets in synthetic and medicinal chemistry due to their significant biological activities. Quinoxaline-1,4-di-N-oxide derivatives have shown to improve the biological results and are endowed with anti-viral, anti-cancer, anti-bacterial, and anti-protozoal activities with application in many other therapeutic areas.Category: quinoxaline

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

 

Dhameliya, Tejas M. et al. published their research in Journal of Organic Chemistry in 2017 | CAS: 55687-34-8

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines are important class of heterocyclic compounds, associated with wider pharmacological applications. Modifying quinoxaline structure it is possible to obtain a wide variety of biomedical applications, namely antimicrobial activities and chronic and metabolic diseases treatment.Product Details of 55687-34-8

Rationalization of Benzazole-2-carboxylate versus Benzazine-3-one/Benzazine-2,3-dione Selectivity Switch during Cyclocondensation of 2-Aminothiophenols/Phenols/Anilines with 1,2-Biselectrophiles in Aqueous Medium was written by Dhameliya, Tejas M.;Chourasiya, Sumit S.;Mishra, Eshan;Jadhavar, Pradeep S.;Bharatam, Prasad V.;Chakraborti, Asit K.. And the article was included in Journal of Organic Chemistry in 2017.Product Details of 55687-34-8 This article mentions the following:

The cyclocondensation reaction of 2-aminothiophenols with 1,2-biselectrophiles such as Et glyoxalate and di-Et oxalate in aqueous medium leads to the formation of benzothiazole-2-carboxylates via the 5-endo-trig process contrary to Baldwin’s rule. The reaction of 2-aminophenols/anilines produced the corresponding benzazine-3-ones or benzazine-2,3-diones via the 6-exo-trig process in compliance with Baldwin’s rule. The mechanistic insights of these cyclocondensation reactions using the hard-soft acid-base principle, quantum chem. calculations (d. functional theory), and orbital interaction studies rationalize the selectivity switch of benzothiazole-2-carboxylates vs. benzazine-3-ones/benzazine-2,3-diones. The presence of water facilitates these cyclocondensation reactions by lowering of the energy barrier. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Product Details of 55687-34-8).

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines are important class of heterocyclic compounds, associated with wider pharmacological applications. Modifying quinoxaline structure it is possible to obtain a wide variety of biomedical applications, namely antimicrobial activities and chronic and metabolic diseases treatment.Product Details of 55687-34-8

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

 

Zhao, Bin et al. published their research in Tetrahedron Letters in 2019 | CAS: 55687-34-8

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. The antitumoral properties of quinoxaline compounds have been of interest. Recently, quinoxaline and its analogs have been investigated as the catalyst’s ligands.Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one

Visible-light-driven cyanoalkylation of quinoxalinones using cyclobutanone oxime esters as the radical precursors was written by Zhao, Bin;Kong, Xianqiang;Xu, Bo. And the article was included in Tetrahedron Letters in 2019.Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one This article mentions the following:

We have developed a versatile visible-light-driven cyanoalkylation of quinoxalinones under mild conditions. First, the cyanoalkyl radicals are generated from readily available cyclobutanone oxime esters under blue light irradiation Then the generated radicals react with heterocycles such as quinoxalinones to give the final cyanoalkylation products. The protocol tolerates a wide range of functional groups. Our cyanoalkylation protocol does not need cyanide-based reagents and also does not need external oxidants. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one).

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. The antitumoral properties of quinoxaline compounds have been of interest. Recently, quinoxaline and its analogs have been investigated as the catalyst’s ligands.Application In Synthesis of 6-Bromoquinoxalin-2(1H)-one

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

 

Yamamoto, Takakazu et al. published their research in Journal of the American Chemical Society in 1996 | CAS: 55687-34-8

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Compounds possessing quinoxaline derivatives were bestowed with a variety of significant biological properties such as antiviral, antimalarial, anticancer, DNA intercalation, DNA duplex stabilization, and many others. Modifying quinoxaline structure it is possible to obtain a wide variety of biomedical applications, namely antimicrobial activities and chronic and metabolic diseases treatment.Related Products of 55687-34-8

Preparation of New Electron-Accepting 蟺-Conjugated Polyquinoxalines. Chemical and Electrochemical Reduction, Electrically Conducting Properties, and Use in Light-Emitting Diodes was written by Yamamoto, Takakazu;Sugiyama, Kiyoshi;Kushida, Takashi;Inoue, Tetsuji;Kanbara, Takaki. And the article was included in Journal of the American Chemical Society in 1996.Related Products of 55687-34-8 This article mentions the following:

Dehalogenation polycondensation of 5,8-dibromoquinoxaline derivatives and 2,6-dibromoquinoxaline with zero-valent Ni complex gives a series of 蟺-conjugated polyquinoxalines with mol. weight of 6 脳 103-260 脳 103. The polymers are electrochem. reduced (or n-doped) with an E掳 value of -1.75 to -2.35 V vs Ag/Ag+ and converted into elec. conducting materials with a conductivity of 1 脳 10-4 to 7 脳 10-3 S cm-1 by chem. reduction Poly(quinoxaline-5,8-diyl)s with aromatic substituents give strong fluorescence with emission peaks at 450-520 nm in solutions as well as in cast films. A light-emitting diode (LED), ITO/polymer/Mg(Ag) (polymer = poly(2,3-diphenylquinoxaline-5,8-diyl)), emits blue-green light (位max at about 500 nm). Introduction of hole-transporting layers such as vacuum-deposited or spin-coated thin layers of poly(thiophene-2,5-diyl), poly(p-phenylene), and poly(N-vinylcarbazole) between ITO and the light-emitting layer enhances electroluminescence efficiency by about 2 orders of magnitude. Polyquinoxalines have an ionization potential of 5.83 卤 0.11 eV and a band gap of 2.56 卤 0.26 eV. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Related Products of 55687-34-8).

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Compounds possessing quinoxaline derivatives were bestowed with a variety of significant biological properties such as antiviral, antimalarial, anticancer, DNA intercalation, DNA duplex stabilization, and many others. Modifying quinoxaline structure it is possible to obtain a wide variety of biomedical applications, namely antimicrobial activities and chronic and metabolic diseases treatment.Related Products of 55687-34-8

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

 

Xu, Jun et al. published their research in Journal of Organic Chemistry in 2021 | CAS: 55687-34-8

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines are important class of heterocyclic compounds, associated with wider pharmacological applications. Quinoxalines are used in the treatment of bacterial, cancer, and HIV infections. Moreover, varenicline, a clinical drug is used for treating nicotine addiction, also contains quinoxaline moiety.Reference of 55687-34-8

Photo-Induced Cross-Dehydrogenative Alkylation of Heteroarenes with Alkanes under Aerobic Conditions was written by Xu, Jun;Cai, Heng;Shen, Jiabin;Shen, Chao;Wu, Jie;Zhang, Pengfei;Liu, Xiaogang. And the article was included in Journal of Organic Chemistry in 2021.Reference of 55687-34-8 This article mentions the following:

A Minisci-type cross-dehydrogenative alkylation in an aerobic atm. using abundant and inexpensive cerium chloride as a photocatalyst and air as an oxidant was reported. This photoreaction exhibited excellent tolerance to functional groups and was suitable for both heteroarene and alkane substrates under mild conditions, generating the corresponding products in moderate-to-good yields. This method provided an alternative approach for the late-stage functionalization of valuable substrates. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Reference of 55687-34-8).

6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines are important class of heterocyclic compounds, associated with wider pharmacological applications. Quinoxalines are used in the treatment of bacterial, cancer, and HIV infections. Moreover, varenicline, a clinical drug is used for treating nicotine addiction, also contains quinoxaline moiety.Reference of 55687-34-8

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider