Discovery of 2,3-Dichloroquinoxaline

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Computational and electrochemical analysis on quinoxalines as corrosion inhibitors for mild steel in acidic medium

In this investigation, quinoxaline derivatives namely, 2-(5-(2-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)naphtho[2,3-d]thiazole (CPTQ) and 2-(3,5-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)naphtho[2,3-d]thiazole (DPTQ) were synthesized and applied as corrosion inhibitors for mild steel (MS) in15% HCl solution. The corrosion inhibition behaviour of CPTQ and DPTQ was studied through weight loss measurement, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). The maximum corrosion inhibition efficiency of DPTQ and CPTQ was found to be 96.01 and 95.62%, respectively at 100 ppm concentration and 303 K temperature. Potentiodynamic polarization studies showed that CPTQ and DPTQ act as mixed type inhibitors. Surface morphology of uninhibited and inhibited MS specimens was characterized using AFM and SEM studies. DFT, molecular dynamic simulations and calculation of Fukui functions were performed for correlation of theoretical parameters with the experimental results.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1530 | ChemSpider

Discovery of 18514-76-6

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A New Route to Indolo<3,2-b>isoquinolines

2-Phenylindole-3-carbaldoximes (2a-d) on cyclization with alcoholic sulphuric acid give delta-carbolines, indolo<3,2-b>-isoquinolines (5a-d) and not the gamma-carbolines.This constitutes a new route to delta-carbolines.

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Quinoxaline | C8H6N857 | ChemSpider

Simple exploration of 2,3-Dichloroquinoxaline

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 2,3-Dichloroquinoxaline, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2

Synthesis and characterization of polyaromatic azine derivatives of (eta5-C5H5) Fe(CO)2 and (eta5-C9H7) Fe(CO)2

The synthesis and characterization of 14 monometallic derivatives of quinoline, quinoxaline, quinazoline and tetraazolo<1,5-A>quinoline and a bimetallic derivative of quinoxaline are reported. These species were prepared in 11 to 88% isolated yields by metathesis reactions between NaFp or NaFp? (where Fp = (eta5 – C5H5)Fe(CO)2 and Fp? = (eta5 – indenyl)Fe(CO)2 ) and the appropriate chlorine substituted polyaromatic azines. These reactions are highly regioselective and generally produce a single organometallic product having the organometallic substituent(s) bonded to the more highly activated azine ring. The structures of three representative examples were confirmed by their X-ray crystal structures, which are reported for the title complexes 4-[(eta5-cyclopentadienyl)irondicarbonyl]-7-chloroquinoline (C16H10ClFeNO2; a = 7.608(1)A, b = 12.006(1)A, c = 15.664(1)A, V = 1431A3; orthorhombic; P212121; Z =4), 2-[(eta5-cyclopentadienyl)irondicarbonyl]-3-chloroquinoxaline (C15H9ClFeN2O2; a = 15.291(3) A, b = 6.561(2) A, c = 14.541(4) A, beta = 106.891(21), V= 1395.9A3; monoclinic; P21/c; Z = 4), and 2-[(eta5-indenyl)irondicarbonyl]-3-chloroquinoxaline (C19H11ClFeN2O2; a = 19.131(2)A, b = 6.688(1)A, c = 13.515(2) A, beta= 101.569(11), V = 1694.1 A3; monoclinic; P21/c; Z = 4). The bimetallic quinoxaline derivative 2,3-[(C5H5)2Fe2(CO)4]-quinoxaline has orrto-substituted organometallic groups and the spectroscopic data suggest that it has an unusual structure in solution, perhaps involving bridging cyclopentadienyl and carbonyl ligands.

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Quinoxaline | C8H6N1362 | ChemSpider

Some scientific research about 2213-63-0

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Reactions of Benzothiohydrazide as a Bidentate Nucleophile

Benzothiohydrazide acts as a 1,4-bidentate nucleophile under basic conditions, and condenses with suitably substituted pyridines, pyrimidines and quinoxalines to yield ring-fused-1,3,4-thiadiazines unsubstituted on the 4-nitrogen position.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1319 | ChemSpider

Properties and Exciting Facts About 2,8-Dichloroquinoxaline

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120258-69-7, Name is 2,8-Dichloroquinoxaline, belongs to quinoxaline compound, is a common compound. name: 2,8-DichloroquinoxalineIn an article, once mentioned the new application about 120258-69-7.

MACROCYCLES AS PIM INHIBITORS

The invention relates to compounds o f formula (1), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of Pirn kinase related conditions and diseases, preferably cancer.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1686 | ChemSpider

Can You Really Do Chemisty Experiments About 5-Nitroquinoxaline

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A trifluoromethyl substituted 3, 3′ – double (2 – phenyl-indolyl) methane compound synthesis method (by machine translation)

The invention belongs to the technical field of chemical synthesis of the fluorine, relates to a synthetic trifluoromethyl substituted 3, 3 ‘- double (2 – phenyl-indolyl) methane compound of method, in order to 2 – phenyl indole as substrate, trifluoromethyl bromide as the alkyl radical source, in under the action of the Cu catalyst, di-tert-butyl peroxide DTBP or too […] diisopropyl benzene as the oxidizing agent, the tertiary butyl alcohol potassium, potassium […] or methanol as alkali, trifluoro methane sulfonic acid or trifluoro methane sulfonic acid magnesium silver as the Lewis acid, 1, 2 – dichloroethane as the solvent under the conditions of the DCE, one-step synthesis of trifluoromethyl substituted 3, 3’ – double (2 – phenyl-indolyl) methane compound. The synthesis method has the operation is simple, cheap and easy to obtain, the diversification of the product and the like. (by machine translation)

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Quinoxaline | C8H6N818 | ChemSpider

More research is needed about 2,3-Dichloroquinoxaline

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Synthesis and biological evaluation of new 3-(4-substituted phenyl)aminoquinoxaline derivatives as anticancer agents

Quinoxaline derivatives 4-11 were synthesized and evaluated for their in vitro growth inhibitory activities against liver carcinoma cell line (HEPG2) using the sulforhodiamine B assay. The synthesis was achieved by reaction of 2,3-dichloroquinoxalines 2a,b with 4-aminoacetophenone to give the corresponding compounds 3a,b. Claisen-Schmidt condensation reaction of 3a,b with furfuraldehyde gave enones 4a,b, which were transformed into pyridines 6a,b, 8a,b, isoxazolines 9a,b, pyrazolines 10a-d, and pyrimidines 11a,b via several synthetic routes. Virtual screening was carried out by molecular modeling evaluation of the designed compounds. Biological evaluation of the prepared compounds showed that most of the synthesized compounds exhibit more than 50% growth inhibitory.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1576 | ChemSpider

New explortion of 2,3-Dichloroquinoxaline

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N,N?-Dihydrotetraazapentacenes (DHTA) in thin film transistors

The synthesis and structural properties of three N,N?-dihydrotetraazapentacenes (DHTA) are described. The different substitution pattern (H, F, Cl) of the dihydrotetraazapentacene body exhibited a significant effect on the optical, electronic and morphological properties of the derivatives in thin films. The synthesised materials were investigated as active layers in top gate/bottom contact (BC/TG) transistors. The transistor performance of the dichlorinated derivative was almost independent on the processing conditions with an average hole mobility of ?0.04 cm2 V-1 s-1 and best mobility values ranging from 0.07 to 0.11 cm2 V-1 s-1. Each of the three derivatives was found to exhibit an individual packing motif in solution grown crystals, determined by single crystal X-ray analysis. Surprisingly, for all three materials a different polymorph formed in spin cast films explaining the observed morphology and FET performance.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1497 | ChemSpider

The important role of 1448-87-9

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 1448-87-9, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1448-87-9, Name is 2-Chloroquinoxaline, molecular formula is C8H5ClN2

Visible-light mediated carbamoyl radical addition to heteroarenes

The generation of carbamoyl radicals, followed by their addition to heteroarenes, was performed under mild conditions through a metal-free photocatalyzed decarboxylation of oxamic acids. The process has been applied to the carbamoylation of heteroaromatic bases using alpha-aminoacid-derived oxamic acids, leading to the corresponding amides without racemization.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N602 | ChemSpider

Brief introduction of Quinoxaline-2,3(1H,4H)-dione

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Related Products of 15804-19-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 15804-19-0, Name is Quinoxaline-2,3(1H,4H)-dione, molecular formula is C8H6N2O2. In a Article£¬once mentioned of 15804-19-0

Effect of heat curing on antifungal activities of anise oil and garlic oil against Aspergillus niger on rubberwood

The effect of heat curing (30-100 C) on the antifungal activity of rubberwood impregnated with anise oil and garlic oil (10-100 mul ml-1) against Aspergillus niger was examined. Essential oil constituents left within the rubberwood after the heat curing and after incubation were analyzed by GC-MS. Response surface methodology (RSM) with a central composite face-centered (CCF) design was employed to evaluate the time needed for initiation of mold growth. The mathematical models containing only significant parameters (p ? 0.05) as functions of treatment temperature and essential oil concentration were obtained. Heat curing adversely and positively influenced the antifungal activities of anise oil and garlic oil, respectively. Such thermal effect was more pronounced at a higher concentration of essential oil. Decomposition of trans-anethole and estragole in anise oil and formation of diallyl disulfide in garlic oil by heat was proposed as the agent responsible for temperature dependencies of the essential oil antifungal activities observed.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N360 | ChemSpider