Tag: M.W:100-200

1593-08-4, 2-Formylquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a mixture of thiazolidine-2,4-dione or rhodanine(0.13 g, 1 mmol), aliphatic/aromatic aldehyde (1 mmol), and ethanol (4 ml), a portion of Fe3O4/SiO2-NH2/Cu(II) (0.15 g) was added and the mixture stirred under reflux for the required time (Table 2). The progress of the reaction was monitored by TLC (n-hexane/EtOAc, 2:1). After completion of the reaction, EtOH (3 ml) was added and the nanocatalyst was separated by an external magnet. The crude product was recrystallized from EtOH., 1593-08-4

1593-08-4 2-Formylquinoxaline 594088, aquinoxaline compound, is more and more widely used in various.

Reference£º
Article; Akhavan, Malihe; Foroughifar, Naser; Pasdar, Hoda; Khajeh-Amiri, Alireza; Bekhradnia, Ahmadreza; Transition Metal Chemistry; vol. 42; 6; (2017); p. 543 – 552;,
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74003-63-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.74003-63-7,3-Methylquinoxaline-2-carboxylic acid,as a common compound, the synthetic route is as follows.

The solid (0.10 g, 0.53 mmol) was slurried in dichloromethane and oxalyl chloride (56 muL, 0.64 mmol) was added at 0 C. The mixture was warmed to room temperature and stirred for 1 hour, then concentrated to a tan solid (62 mg, 57%).

The synthetic route of 74003-63-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Pfizer Inc; US2005/43292; (2005); A1;,
Quinoxaline – Wikipedia
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1865-11-8, Methyl quinoxaline-2-carboxylate is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a stirred solution of methyl quinoxaline-2-carboxylate (1-a) (4.0 g, 21 mmol) in ethanol (50 mL) was added acetic acid (1.2 mL, 21 mmol) and Pd/C (10 wtpercent, 2.2 g, 21 mmol). The solution was degassed and then stirred under 5 kg pressure of hydrogen for 36 hours. The mixture was filtered through CELITE (diatomaceous earth) bed and the CELITE bed waswashed with excess methanol. The combined filtrate was concentrated under reduced pressure and the mixture was purified by column chromatography (25 ? 50percent ethyl acetate in petroleum ether) to provide the titled compound (1-b), which gave a proton NMR spectra consistent with theory a mass ion [ES+] of 193.2 for [M + H]., 1865-11-8

The synthetic route of 1865-11-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; MERCK SHARP & DOHME CORP.; BESHORE, Douglas, C.; WU, Wen-Lian; (45 pag.)WO2017/99969; (2017); A1;,
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6298-37-9, Quinoxalin-6-amine is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To the reaction vessel was added example 40 (36 mg, 0.10 mmol), 6-aminoquinoxaline [6298-37-9] (15 mg, 0.10 mmol), COMU (53 mg, 0.12 mmol), DCM (1.3 mL) and DIPEA (17 m, 0.10 mmol). The reaction mixture was stirred at r.t. overnight. To the reaction mixture was added water (1.2 mL) and the mixture was filtered through a phase separator. The aqueous phase was further extracted with DCM (2 x 400 m), the organic phases were combined and concentrated in vacuo to yield the crude product which was purified by preparative HPLC (basic) to afford the title compound (0.0092g, 19%). LCMS (ES+) [M+H]+490.1892, RT 4.72 minutes (Method 20)., 6298-37-9

6298-37-9 Quinoxalin-6-amine 0, aquinoxaline compound, is more and more widely used in various.

Reference£º
Patent; UCB BIOPHARMA SRL; CHOVATIA, Prafulkumar Tulshibhai; CONNELLY, Rickki Lee; FRANKLIN, Richard Jeremy; HASLETT, Gregory William; HENRY, Alistair James; MADDEN, James; NEUSS, Judi Charlotte; NORMAN, Timothy John; PHILPS, Oliver; PITT, William Ross; RAMPALAKOS, Konstantinos; SELBY, Matthew Duncan; SELVARATNAM, Suganthan; TRANI, Giancarlo; ZHU, Zhaoning; (768 pag.)WO2019/243550; (2019); A1;,
Quinoxaline – Wikipedia
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