Tag: M.W:100-200

Brzezinski, Bogumil; Zundel, Georg published the article 《Influence of solvents on intramolecular hydrogen bonds with large proton polarizability》. Keywords: hydrogen bond intramol NMR; proton polarizability hydrogen bond NMR.They researched the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ).SDS of cas: 1127-45-3. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1127-45-3) here.

A large number of compounds with intramol. hydrogen bonds with great proton polarizability were studied by 1H NMR in solvents of various polarities. With the homoconjugated hydrogen bonds, small changes of the chem. shift of the hydrogen-bonded proton are observed with increasing polarity of the solvent, whereby the signal shifts toward lower field. This effect is explained by increasing removal of the counterions from the homoconjugated hydrogen bonds and thus, by decreasing induced dipole interaction of the counterions and the hydrogen bonds with great proton polarizability. In the case of heteroconjugated hydrogen bonds analogous but much greater shifts are observed They are explained by a shift of the OH···N ⇌ O-···H+N equilibrium to the right-hand side with increasing polarity of the solvent. With hydrogen bonds showing no great proton polarizability these effects do not occur.

After consulting a lot of data, we found that this compound(1127-45-3)SDS of cas: 1127-45-3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Yang, Kai; Qiu, Yatao; Li, Zheng; Wang, Zhaoyang; Jiang, Sheng published an article about the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3,SMILESS:OC1=CC=CC2=CC=C[N+]([O-])=C12 ).Recommanded Product: 1127-45-3. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1127-45-3) through the article.

Several new ligands were designed to promote copper-catalyzed Ullman C-N coupling reactions. In this group, 8-hydroxyquinoline-N-oxide was found to serve as a superior ligand for CuBr-catalyzed coupling reactions of aryl iodides, bromides, and chlorides with aliphatic amines and N-heterocycles under a low catalyst loading (1% [Cu] mol). Reactions with the inexpensive catalytic system display a high functional group tolerance as well as excellent chemoselectivity.

After consulting a lot of data, we found that this compound(1127-45-3)Recommanded Product: 1127-45-3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Hsu, Fu-Lian; Hamada, Akihiko; Booher, Mark E.; Fuder, H.; Patil, P. N.; Miller, Duane D. researched the compound: (S)-Propane-1,2-diamine dihydrochloride( cas:19777-66-3 ).Safety of (S)-Propane-1,2-diamine dihydrochloride.They published the article 《Optically active derivatives of imidazolines. α-Adrenergic blocking properties》 about this compound( cas:19777-66-3 ) in Journal of Medicinal Chemistry. Keywords: imidazoline stereoisomer preparation adrenergic blocker. We’ll tell you more about this compound (cas:19777-66-3).

The title compounds I (R and R1 = H, Me, or PhCH2; R2 = 1-naphthylmethyl, PhCH2, or 2,6-dichloroaniline) as salts were prepared from an optically active 1,2-diamine-2HCl and an imino ester HCl, and converted to a stable solid salt. I were evaluated for α-adrenergic activity on rabbit aortic strips. Compared to naphazoline or tolazoline, substitution of a Me or PhCH2 at the 4 position of the imidazoline ring resulted in moderate α-blocking activity with no apparent stereoselectivity with such substitution.

After consulting a lot of data, we found that this compound(19777-66-3)Safety of (S)-Propane-1,2-diamine dihydrochloride can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Icelli, Orhan; Erzeneoglu, Salih published an article about the compound: Nickel(ii)fluoridetetrahydrate( cas:13940-83-5,SMILESS:[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Ni+2].[F-].[F-] ).Recommanded Product: 13940-83-5. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:13940-83-5) through the article.

Effective at. numbers of V2O3, VO2, VF3, NH4VO3, VF4, NiF2, NiCl2, NiF2·4H2O, NiCl2·6H2O, and Ni(ClO4)2·6H2O were measured in the x-ray energy range of 15.746-40.930 keV using an Si(Li) detector. The measured values are compared with the theor. ones calculated using WinXcom.

Although many compounds look similar to this compound(13940-83-5)Recommanded Product: 13940-83-5, numerous studies have shown that this compound(SMILES:[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Ni+2].[F-].[F-]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Desiderato, R.; Terry, J. C.; Freeman, G. R.; Levy, H. A. published the article 《Molecular and crystal structure of 8-hydroxyquinoline N-oxide》. Keywords: structure quinolinol oxide.They researched the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ).Category: quinoxaline. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1127-45-3) here.

The structure of 8-hydroxyquinoline N-oxide was determined from diffractometer data by a direct method. The compound crystallizes in the monoclinic system with space group P21/c. The cell data are: a 12.1364(4), b 4.9211(2), c 13.1384(4) Å, β 109.26(1)°, d.(calculated)=1.449, d.(exptl.)=1.46, Z=4. The structure was solved by a direct method. 1528 reflections were used in a full-matrix least-squares refinement. R was reduced to a final value of 0.053. Bond lengths between non-H atoms have estimated standard derivations (e.s.d.’s) between 0.002 and 0.003 Å. The e.s.d.’s of the various bond angles (non-H atoms) range from 0.01 to 0.02°. Distances and angles involving the H atoms have e.s.d.’s of 0.02 Å and 1°, resp. The 2 C-N distances of the quinoline ring are unusually long, and the quinoline moiety is surprisingly similar to naphthalene in terms of bond distances and angles. The inductive effect of the N-O group may in part be responsible for the C-N lengthenings. The hydroxyl H atom is bonded to the dative O atom via a short intramol. H bond. The direct relation between the N-O dative bond distance and the strength of a H bond to the dative O atom appears to be substantiated in this study.

Although many compounds look similar to this compound(1127-45-3)Category: quinoxaline, numerous studies have shown that this compound(SMILES:OC1=CC=CC2=CC=C[N+]([O-])=C12), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Gupta, Rajeshwar Dayal; Manku, G. S.; Bhat, A. N.; Jain, Bimal D. published the article 《Spectrophotometric determination of ruthenium(III) and iridium(IV) with 8-hydroxyquinoline N-oxide》. Keywords: photometry ruthenium iridium determination; hydroxyquinoline oxide ruthenium iridium determination; ruthenium determination; iridium determination; stability hydroxyquinoline oxide metal complex; complex metal hydroxyquinoline oxide stability.They researched the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ).Name: 8-Hydroxyquinoline 1-oxide. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1127-45-3) here.

The spectrophotometric characteristics and the stability constants of the yellow to brown 1:1 and 1:2 complexes of Pt metals with 8-hydroxyquinoline N-oxide (I) (existing as chloro mixed-ligand complexes) have been investigated. I can be used as a spectrophotometric reagent for Ru(II) and Ir(IV).

Although many compounds look similar to this compound(1127-45-3)Name: 8-Hydroxyquinoline 1-oxide, numerous studies have shown that this compound(SMILES:OC1=CC=CC2=CC=C[N+]([O-])=C12), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Synthesis and study of N-oxides of heterocyclic compounds. I. N-Oxides of derivatives of morphine, tetra-hydroisoquinoline, and quinoline》. Authors are Khaletskii, A. M.; Pesin, V. G.; Tsin, Chshou.The article about the compound:8-Hydroxyquinoline 1-oxidecas:1127-45-3,SMILESS:OC1=CC=CC2=CC=C[N+]([O-])=C12).Reference of 8-Hydroxyquinoline 1-oxide. Through the article, more information about this compound (cas:1127-45-3) is conveyed.

cf. Ochiai, C.A. 48, 3359i. Heating 8.4 g. codeine with 45 ml. 3% H2O2 at 50-60° gave after evaporation 8 g. codeine N-oxide, m. 206-8° (H2O); HCl salt, m. 214-17° (EtOH). To 5 g. dihydrohydroxycodeinone-HCl was added 10 ml. 10% NaOH yielding 93% dihydrohydroxycodeinone, m. 213-16°, which with 3% H2O2 as above gave 46.2% dihydrohydroxycodeinone N-oxide, decompose 152-3°, which gives a red color with Ac2O; picrate, m. 190-2°; HCl salt, m. 167-8°. The oxide treated with SO2 in warm EtOH gave 62.5% C18H23O8NS, decompose 169-70°, which was evidently an isomer of dihydrohydroxycodeinone sulfate; with BaCl2 solution it readily gave BaSO4; hydrolysis with 10% NaOH gave the original dihydrohydroxycodeinone, m. 207-9° (sulfate, m. 138-9°). Salsolidine (3 g.) in 20 ml. Me2CO and 30 ml. H2O treated with 2.5 ml. 30% H2O2 after several days at room temperature gave 15.48% N-hydroxysalsolidine, m. 100-1° (aqueous EtOH), which reduced Fehling and Tollens reagents. Similarly, N-methylsalsolidine gave N-methylsalsolidine N-oxide picrate, m. 133-4° (aqueous EtOH); HCl salt analog, decompose 162-3°. Oxidation of salsoline with 3% H2O2 in AcOH or with BzO2H in CHCl3 either gave no reaction or failed to yield any definite products. N-Methylsalsoline with aqueous H2O2 at room temperature in 3 days gave N-methylsalsoline N-oxide, m. 183° (EtOH); HCl salt, m. 186°. Oxidation of 8-hydroxyquinoline in CHCl3 with BzO2H with cooling gave yellow 8-hydroxyquinoline N-oxide, m. 137-8° (H2O); the same formed on oxidation with 30% H2O2 in AcOH-Ac2O at 40-5° in 3 hrs., but with 30% H2O2-AcOH in 2 hrs. only the starting material was recovered. 8-Hydroxyquinoline N-oxide treated with alc. KOH and Etl at reflux gave 8-ethoxyquinoline N-oxide, isolated as picrate, m. 135-8°; the same formed on treatment of 8-ethoxyquinoline with AcOH-Ac2O-30% H2O2 at 45-50°; HCl salt, m. 158°; free oxide, m. 61-2°. Similarly 2-phenylquinoline-4-carboxylic acid and AcOH-H2O2 gave 76% N-oxide, m. 244°, and 15% benzoylanthranilic acid, m. 170-2°. Oxidation of 2-phenylquinoline-4-carboxylic acid with BzO2H in CHCl3 in 2 days gave no evident reaction, the same being true of oxidation with 25% H2O2 in EtOH-Me2CO at 50°. Reduction of 2-phenylquinoline-4-carboxylic acid N-oxide with Na hydrosulfite in aqueous EtOH gave the original 2-phenylquinoline-4-carboxylic acid, m. 205-7°.

Although many compounds look similar to this compound(1127-45-3)Reference of 8-Hydroxyquinoline 1-oxide, numerous studies have shown that this compound(SMILES:OC1=CC=CC2=CC=C[N+]([O-])=C12), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Nayak, Pabitra K.; Agarwal, Neeraj; Ali, Farman; Patankar, Meghan P.; Narasimhan, K. L.; Periasamy, N. published an article about the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3,SMILESS:OC1=CC=CC2=CC=C[N+]([O-])=C12 ).Quality Control of 8-Hydroxyquinoline 1-oxide. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1127-45-3) through the article.

Synthesis, structure, optical absorption, emission and electroluminescence properties of a new blue emitting Al complex, namely, bis-(2-amino-8-hydroxyquinolinato), acetylacetonato Al(III) are reported. Multilayer OLED using the Al complex showed blue emission at 465 nm, maximum brightness of ∼425 cd/m2 and maximum current efficiency of 0·16 cd/A. Another multilayer OLED using the Al complex doped with phosphorescent Ir complex showed ‘white’ light emission, CIE coordinate (0·41, 0·35), maximum brightness of ∼970 cd/m2 and maximum current efficiency of 0·53 cd/A.

Although many compounds look similar to this compound(1127-45-3)Quality Control of 8-Hydroxyquinoline 1-oxide, numerous studies have shown that this compound(SMILES:OC1=CC=CC2=CC=C[N+]([O-])=C12), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Bioorganic & Medicinal Chemistry Letters called Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives, Author is Xu, Yulan; Sheng, Chunquan; Wang, Wenya; Che, Xiaoying; Cao, Yongbing; Dong, Guoqiang; Wang, Shengzheng; Ji, Haitao; Miao, Zhenyuan; Yao, Jianzhong; Zhang, Wannian, which mentions a compound: 57825-30-6, SMILESS is CCC1=CC=C(CBr)C=C1, Molecular C9H11Br, Name: 1-(Bromomethyl)-4-ethylbenzene.

In an attempt to find novel azole antifungal agents with improved activity and broader spectrum, computer modeling was used to design a series of new azoles with piperidin-4-one O-substituted oxime side chains. Mol. docking studies revealed that they formed hydrophobic and hydrogen-bonding interactions with lanosterol 14α-demethylase of Candida albicans (CACYP51). In vitro antifungal assay indicates that most of the synthesized compounds showed good activity against tested fungal pathogens. In comparison with fluconazole, itraconazole and voriconazole, several compounds (such as I, R = H, 3-Cl, 2-F) show more potent antifungal activity and broader spectrum, suggesting that they are promising leads for the development of novel antifungal agents.

Although many compounds look similar to this compound(57825-30-6)Name: 1-(Bromomethyl)-4-ethylbenzene, numerous studies have shown that this compound(SMILES:CCC1=CC=C(CBr)C=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 1-(Bromomethyl)-4-ethylbenzene, is researched, Molecular C9H11Br, CAS is 57825-30-6, about Synthesis and biological studies of novel 2-(4-substitutedbenzylthio)-5-amino-6-(benzo[d]thiazol-2-yl)-7-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one derivatives.Electric Literature of C9H11Br.

A series of novel 2-(4-substitutedbenzylthio)-5-amino-6-(benzo[d]thiazol-2-yl)-7-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one derivatives were synthesized and evaluated for their antibacterial and antifungal activity. All the derivatives were efficiently synthesized in four steps. The structure of the newly synthesized compounds was elucidated by their IR, 1H-NMR, 13C NMR, LCMS mass spectra and elemental anal.

Although many compounds look similar to this compound(57825-30-6)Electric Literature of C9H11Br, numerous studies have shown that this compound(SMILES:CCC1=CC=C(CBr)C=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider