1865-11-8, Methyl quinoxaline-2-carboxylate is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
[1500] a solution of compound 356a (2.5 g, 13.29 mmol) in CH3COOC2H5 (60 ml) was added t-BuOK (1.94 g, 17.28 mmol). The mixture was stirred for 0.25 hour at 25¡ãc. The mixture was quenched with H2O (50 ml). The organic layer was separated and the aqueous was extracted with ea (50 ml x 3). The organic phases were combined, dried with anhydrous Na2SO4, filtered and evaporated. The residue was purified by flash chromatography (pe: ea =20/1 to 10/1) to afford compound 356b (2.45 g, 75.48percent yield) as pale yellow solid. 1H NMR (CDCl3, 400 mhz) delta 9.57 – 9.33 (m, 1h), 8.19 – 8.06 (m, 2h), 7.96 – 7.74 (m, 2h), 4.35 – 4.26 (m, 2h), 4.24 – 4.13 (m, 2h), 1.28 – 1.18 (m, 3h).
1865-11-8, As the paragraph descriping shows that 1865-11-8 is playing an increasingly important role.
Reference£º
Patent; BLADE THERAPEUTICS, INC.; BUCKMAN, Brad, Owen; YUAN, Shendong; ADLER, Marc; EMAYAN, Kumaraswamy; MA, Jingyuang; (687 pag.)WO2018/64119; (2018); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider